Protein Info for HMPREF1078_RS14760 in Parabacteroides merdae CL09T00C40

Annotation: alpha-L-rhamnosidase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 804 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF17389: Bac_rhamnosid6H" amino acids 402 to 650 (249 residues), 82.8 bits, see alignment E=4.5e-27 PF17390: Bac_rhamnosid_C" amino acids 725 to 797 (73 residues), 29.5 bits, see alignment E=8.1e-11

Best Hits

KEGG orthology group: None (inferred from 73% identity to pdi:BDI_1796)

Predicted SEED Role

"Alfa-L-rhamnosidase (EC 3.2.1.40)" in subsystem L-rhamnose utilization (EC 3.2.1.40)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.40

Use Curated BLAST to search for 3.2.1.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (804 amino acids)

>HMPREF1078_RS14760 alpha-L-rhamnosidase C-terminal domain-containing protein (Parabacteroides merdae CL09T00C40)
MKTRVLIFLFMLCSLSLGAQIRLEGYRQTDINPELLTGRWKARWISMPGEPANVYGVYHM
RKTFELDEVPSRFIVHVTADNRYKLYLNGRFVSLGPARGDIYNWNFETVDLAPYLIKGKN
VLAAVIWNYAEQKPVAQISFNQTGFLLQGNTEVETVVNTDASWLCMKNEAYAPWHKPVLG
YYVAGPGEFLSASKYPWGWEQSAYDDSKWLPAHTGIEGGVKGSRDYPGRLLVPCPIPPMD
LLSERFEAVRISEGVKIPVGFLKTKTSLTVPANSKVHLLLDNGKLTTGYLSLLFSRGKNA
EITIAYAEALYEGKELGTTKSYSFPAKGNRDEVEGKRFIGYEDKVIADGGEGRDFTTLWW
RTWRYVDLTISTADEPLVLEDVYGTFSAYPFRCEIAFSAPGHDELNKMLEIGWRTARLCA
NETYMDCPYYEQLQYFGDTRIQAMITLYNTHDAYMVKNAIEQGRQSVVADGITMSRYPSS
LHQFISSFSLWWICMGHDYWMYRGDEAYMKTLLPAYRGVLSWYEQWLKRDHSLGYVPHWF
FADWAVGFQSGEPVREKDGNSAFQDLVYILTLESAAEMERAFGIPSIADHYTQIASAIRG
TIREKYWDATRGLFADTYDHRSFSQHVNSLAILAGIVTGEEATRVMERTLNDSSLIQATI
YFRYYVHQALKVAGMGDHLLDNLQIWRDQMALGLTTWAEMPEPTRSDCHAWGASPNIEFF
RILLGIDSNAPGFKSIRIAPSLGDLKEVSGTMPHPVGSVTASYKLDKKGKLTARLILPTG
TDGVFVWKGKEYQLKSGEQVLTVE