Protein Info for HMPREF1078_RS14695 in Parabacteroides merdae CL09T00C40

Annotation: signal recognition particle protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 TIGR00959: signal recognition particle protein" amino acids 2 to 424 (423 residues), 633.6 bits, see alignment E=8e-195 PF02881: SRP54_N" amino acids 5 to 82 (78 residues), 68.5 bits, see alignment E=9.8e-23 PF00448: SRP54" amino acids 99 to 295 (197 residues), 254.9 bits, see alignment E=9.5e-80 PF02978: SRP_SPB" amino acids 326 to 423 (98 residues), 126.2 bits, see alignment E=1.1e-40

Best Hits

Swiss-Prot: 53% identical to SRP54_BACSU: Signal recognition particle protein (ffh) from Bacillus subtilis (strain 168)

KEGG orthology group: K03106, signal recognition particle subunit SRP54 (inferred from 94% identity to pdi:BDI_0218)

Predicted SEED Role

"Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)" in subsystem Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>HMPREF1078_RS14695 signal recognition particle protein (Parabacteroides merdae CL09T00C40)
MFENLSERLDRSFKLLKGEGKITEINVAETLKDVRKALLDADVNYKVAKGFTDTVKAKAL
GQNVLTSVKPSQLMVKIVHDELADLMGGTATDLDLKGSPAIILMSGLQGSGKTTFSGKLA
NLLKTKKNKKPLLAACDVYRPAAIEQLRVVGEQVGVPVYMELENKNPVAIAMNAIREARA
KGNDVVIVDTAGRLAIDEQMMKEIAAIKSAIQPDETLFVVDSMTGQDAVNTAKEFNERLD
FDGVVLTKLDGDTRGGAALSIRTVVDKPIKFVGTGEKMDALDIFHPERMADRILGMGDIV
SLVERAQEQYDEEEAKRLQKKIAKNQFDFNDFISQIQQIKKMGNLKELASMIPGVGKALK
DVDIDDNAFKSIEAIIYSMTPEERTNPAILNGSRRQRIAKGSGTTIQEVNKLIKQFDETR
KMMRMLTAAKPGSKKFPSFRR