Protein Info for HMPREF1078_RS14655 in Parabacteroides merdae CL09T00C40

Annotation: glycogen debranching enzyme N-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 transmembrane" amino acids 624 to 641 (18 residues), see Phobius details PF12439: GDE_N" amino acids 20 to 240 (221 residues), 282 bits, see alignment E=3e-88 PF06202: GDE_C" amino acids 279 to 636 (358 residues), 236.1 bits, see alignment E=6.1e-74

Best Hits

KEGG orthology group: None (inferred from 88% identity to bvu:BVU_2774)

Predicted SEED Role

"Putative glycogen debranching enzyme, archaeal type, TIGR01561" in subsystem Glycogen metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (646 amino acids)

>HMPREF1078_RS14655 glycogen debranching enzyme N-terminal domain-containing protein (Parabacteroides merdae CL09T00C40)
MSYLKFDKTLMTNLEEALPREILRTNRSGAYHCTTIVDCNTRKYHGLLVIPVPELDDENH
VLLSSLDETVIQHGAEFNLGLHKYQGDNYSPRGHKYIREFECEKVPTTIYRVGGVILKKE
KLFVHHENRILIRYTLLDAHSATTLRLRPFLAFRSVREYTHENAQASREYQVVSNGIKTC
MYPGYPELYMQLNKKNEFHYLPDWYRGIEYPKEQERGYDFNEDLYVPGYFEVEIKKGESI
VFSGGVSEIGTRSLKKTFEDEVEERTPRDTFRHCLINAAHQFLNKQENEFYILAGYPWFK
CRARDLFISLPGLTLAINEVSKFEMVMETACKAIYNFIRNEPSQIKIYEMEHPDILLWAV
WCIQQYAKMVSREACREKYGVLLEDIMRFLCQDKHPNLILHDNGLLYTYGTNRAVTWMNS
TVNGHPVIPRTGYIVEINTLWYNALRFAGELSGEAGNNALAESLGALAEKSGKSFVNVFL
NEYGYLLDYVDGNMMEWSVRPNMIFAVAFDYSPLNSSQKKGVLDIVTKELLTPKGLRSLS
PKSGGYNPNYVGPQIQRDYAYHQGTAWPWLAGFYFEAYLRIYKMSGIGFIERYLIGYEDE
MSSHCIGSISELFDGNPPFKGRGAISFAMNVAEILRILYLLSKYNY