Protein Info for HMPREF1078_RS14390 in Parabacteroides merdae CL09T00C40

Annotation: anaerobic C4-dicarboxylate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 6 to 38 (33 residues), see Phobius details amino acids 49 to 73 (25 residues), see Phobius details amino acids 90 to 116 (27 residues), see Phobius details amino acids 131 to 155 (25 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details amino acids 223 to 243 (21 residues), see Phobius details amino acids 263 to 282 (20 residues), see Phobius details amino acids 293 to 312 (20 residues), see Phobius details amino acids 334 to 353 (20 residues), see Phobius details amino acids 362 to 385 (24 residues), see Phobius details amino acids 415 to 434 (20 residues), see Phobius details PF03605: DcuA_DcuB" amino acids 4 to 370 (367 residues), 513.4 bits, see alignment E=1.6e-158 TIGR00770: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family" amino acids 4 to 435 (432 residues), 542.3 bits, see alignment E=4.9e-167

Best Hits

KEGG orthology group: K07792, anaerobic C4-dicarboxylate transporter DcuB (inferred from 85% identity to pdi:BDI_1977)

Predicted SEED Role

"Anaerobic C4-dicarboxylate transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>HMPREF1078_RS14390 anaerobic C4-dicarboxylate transporter (Parabacteroides merdae CL09T00C40)
MLLQLLFVLIAIIIGARLGGIGLGVLGGLGLAILTFVFGLEPTSPPIDVMLMIVAVIAAA
SCMQAAGGLDLMVKWAEKLLRKNPSKITLLSPLVTYIFTFIAGTGHVAYSVLPVIAEVAT
ETKIRPERPLGIAVIASQQAITASPISAATVALLSMLSGHNISLMDILMISVPCTLIGVL
AGAFCSLHVGKELAEDPEYLRRVANEEFTSDKYRAKGVENHHAALLSVIIFIAATIGIVL
FGSMTELRPWFSLPDGSLRQMQMAHIIEILMLSAAALILLVTRTDGIKAVQGSVFSAGMQ
AVVAIFGIAWMGDTFIGGNMAELKGSIEHIVTEMPWLFGLALFVMSILLFSQAATIRAML
PLGIALGISPYMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTHIGKYVLNHSFMMPGL
VATGVSVALGLLMIQLF