Protein Info for HMPREF1078_RS14385 in Parabacteroides merdae CL09T00C40

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 147 to 169 (23 residues), see Phobius details PF00672: HAMP" amino acids 171 to 219 (49 residues), 43.6 bits, see alignment 8.9e-15 PF00989: PAS" amino acids 236 to 338 (103 residues), 44.8 bits, see alignment E=3.4e-15 PF13426: PAS_9" amino acids 247 to 348 (102 residues), 29.5 bits, see alignment E=2.4e-10 PF00512: HisKA" amino acids 355 to 423 (69 residues), 50.1 bits, see alignment E=6.9e-17 PF02518: HATPase_c" amino acids 470 to 575 (106 residues), 86.6 bits, see alignment E=5e-28

Best Hits

KEGG orthology group: None (inferred from 82% identity to pdi:BDI_0115)

Predicted SEED Role

"Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (576 amino acids)

>HMPREF1078_RS14385 ATP-binding protein (Parabacteroides merdae CL09T00C40)
MDKFLRLKIKTKLTFGIGLLFTMIVLLGGLAVQNITDMSSDTQNILADNYNSLLYSRRML
DALERIKNDPQARAEFEKNLDLQQKNITEIDENVATAHLVAQYEAMHRDLNDTTIQRVRM
ALNDIMSLNMATIYRKSKVAERTADQALLWICIIAVACVLIAFAFLIRLPRSITSPIRKL
TDGILEIANHNYEKRLDLGDNQEFAEVASSFNRMAERLTEYRKSTLADIIQAKKYIEAIV
NSITEPIIGLDRDRSILFANDEALTILNLKRENVMGKSATELALKNDLLRRLVRELIQHD
KKKEPLKIYADDKESYFQAKYIPIHVMDGDGRETEYVGDVILLKNITEFKELDSAKTTFI
STISHELKTPISAILMSLKLLEDKRIGDMNDEQIALAGSIRESSDRLLEITGELLKMTQV
EAGKLQLNPKITKPIELIDYAIKANRVQAERFNCHIEVEYPEKISKLFVDSEKIAWVLTN
LLSNAIHYTPENGRIVIGAHQVDKKVEIFVQDFGKGIDPRYHQSIFDRYFRVPGTKVQGS
GLGLAISKDFVEAHGGTIRVDSEVGKGSTFVITFDV