Protein Info for HMPREF1078_RS14315 in Parabacteroides merdae CL09T00C40

Annotation: M64 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF16217: M64_N" amino acids 23 to 137 (115 residues), 140.1 bits, see alignment E=2.7e-45 PF09471: Peptidase_M64" amino acids 167 to 373 (207 residues), 220.2 bits, see alignment E=3.5e-69 amino acids 374 to 419 (46 residues), 28.8 bits, see alignment 7e-11

Best Hits

KEGG orthology group: None (inferred from 82% identity to pdi:BDI_0092)

Predicted SEED Role

"FIG00898204: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>HMPREF1078_RS14315 M64 family metallopeptidase (Parabacteroides merdae CL09T00C40)
MKTKISLLLLAILCNFSVFAQSDFDKYFEKKSLRVDFALSGNLKSQSAAIQGLREEPVWG
GPVKNLIDKFNYGGYYINVYDKATNKLIYSRGFNTLFEEWRSTEQAKTETQSWTNSASVP
FPKVPIYVEITARDKADMQFHPLLKQEVDPKSIFIDRGKLKANKVHQIQKSGDSTEKVDL
VFIAEGYTADEQEKFVADANRFTEALFATPPFTTRRNDFNVWAVCLVSEESGTDVSGKGI
FKNTALNSGYYTFGVDRYLTTPDMKSIRDAVWNVPCDAIFLLINTDMYGGGGMYNFYACG
TADNPRTPVVFTHEFGHSFAGLADEYFSSEVAYQDFYNLKYEPWEPNITTLVDFGSKWKD
LLPADTPIPTPLDAGHKDKAGVFEGGGYLSKGIYRPMDHCMMRDYAPFCPACSRAILQMV
DFLTDK