Protein Info for HMPREF1078_RS14100 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1051 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 32 to 1051 (1020 residues), 784.7 bits, see alignment E=1.8e-239 PF13620: CarboxypepD_reg" amino acids 32 to 103 (72 residues), 41 bits, see alignment 4.1e-14 PF13715: CarbopepD_reg_2" amino acids 33 to 114 (82 residues), 68.8 bits, see alignment 6.7e-23 PF07715: Plug" amino acids 121 to 228 (108 residues), 68.3 bits, see alignment E=1.6e-22 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 204 to 234 (31 residues), 53.7 bits, see alignment (E = 1.3e-18) PF00593: TonB_dep_Rec" amino acids 436 to 902 (467 residues), 47.9 bits, see alignment E=3.9e-16

Best Hits

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1051 amino acids)

>HMPREF1078_RS14100 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MQKCKLNFLLRFGLISILLGLFVTQSFAQNVTITGVVKDQSGEPLIGVNVMEKGTTNGSI
TDVDGKYSVSVKGGKTILVFSYIGYISQEIPVGNQKTLNVTMKEDTEELEEVVVIGYGTA
KKKDLTGAISTVKAESLEKETPRSVQDLLRANAPGVSIGASVNAEGTASVQIRGKNTLSA
GSDPLYVLDGVIFNGDLSDINPMDVQSIDVLKDASSVAVYGAKAANGVIAITTKKGKTGK
PVVNFNSNFGWVQANSVPEVVDGAGFVKFRQEYSESLLTPEELAAKKGMYDDPRTLGSLG
VDPLTWYNYDQSTPATALPSEEQMLTTWLGRLNFKNIEIQNYLNGVETDWTDLVFQTGFQ
QDYTASISNRTDNFSYFWSMGYADREGVKVGDRFKTFRTRLNLESKVTDFLTIGLNSSFG
TKDKGALSADVGQRTNNSPFTTNEIDDPDSPYRMYPSGDNNTKNPFFDNLYRDRKDMEHK
LNANIYAIVKLPFGFEYQMNFNPYYKWYEYYNHDSSQHPEWAGEGGKSERKNQKTFNWQI
DNIVRWKKEFGKHRVEATFLQNAEKGQFWETIAKASQFTPSDILGYHNIGAGTVPVVSSN
DTYKTGDALMGRLFYSFADRYMVTASVRRDGYSAFGQMNPRATFPAVALGWVFTSEKFME
PASSWLNYGKLRFSWGQNGNRDIGQYDALAKLNSGLHPYIDQNGNIYVTSQIYVDRMANK
GLKWERTSSYNIGLDFSLFNDRLRGSMETYMTETTDLLVDRALPSILGFASVKANLGKLA
NKGFELSLNGDIIRTNDFTWTSSGSFSFNRRKLKSLYGDMEDVLDENGNVIGQKEKDDPK
NGWFIGHDPDQIWDYEFGGVWQLGQEEEASKYGCKPGDFRFIDQDGNGVLDDDDKTFQGY
KTPRFFWSWRNEFIYKDFSLSFMLYSDIGHYDYYNHASNSGGMFDRYSTYDQPRWTPENP
TNEYGRIGSYRFANYYKKKTFVRMDNISLSYAVPKDFLKKFKVQNMRISLTARNPFTITG
WDYFDVEATKKNRDDGLYGMRSYNISFNFTL