Protein Info for HMPREF1078_RS13700 in Parabacteroides merdae CL09T00C40

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 832 transmembrane" amino acids 32 to 54 (23 residues), see Phobius details amino acids 97 to 116 (20 residues), see Phobius details amino acids 128 to 148 (21 residues), see Phobius details amino acids 173 to 192 (20 residues), see Phobius details PF13491: FtsK_4TM" amino acids 30 to 197 (168 residues), 61 bits, see alignment E=2.4e-20 PF17854: FtsK_alpha" amino acids 341 to 441 (101 residues), 110.4 bits, see alignment E=8.6e-36 PF01580: FtsK_SpoIIIE" amino acids 452 to 651 (200 residues), 172.5 bits, see alignment E=1.9e-54 PF09397: FtsK_gamma" amino acids 758 to 818 (61 residues), 96.5 bits, see alignment 1.2e-31

Best Hits

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 75% identity to pdi:BDI_0399)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (832 amino acids)

>HMPREF1078_RS13700 DNA translocase FtsK (Parabacteroides merdae CL09T00C40)
MAKKTTAKQNTNNGESKFKGIRNFFTSERTRFITGLVISIVTIYVGLALISFFFTGGADQ
SKIENIPLSDLVINRGSVENWTGVRGAFLADLLMNRWFGISSFLILFFLGSVGAKLMNLS
RVSLLKRFLFSAAMLIWGSLFFAFIFIRGYEDTFIYLGGQHGYYLSEVMMNNIGIPGTVL
LLVGLFLIVAIFTSKRTIPFLQNVFSFGWLKNRLKRDKSETTEVPEEEEDVEGEAEVYAP
VEKTVAAPQPVAYRETVEENIGPDEYVFDTETEMRKAEVETEVPQKDDFEFEVARGDDPV
VEAGNGNNTIFEVEVPEEEEEFDQSQLGKYDPRLDLSRYMFPTLDLLKFYDSGNVEVNRE
ELEENQQMIKRTLEDFGINIASIKATVGPTVTLYEIIPEAGVRISKIKNLEDDIALSLSA
LQIRIIAPMPGKGTIGIEVPNNKPQTVSMQSVVASRKFQECTYDLPVAIGRTIVNEVFMF
DLCKTPHLLVAGATGQGKSVGLNAIITSLLYKKHPAELKFVMVDPKQVEFSIYSKIERHY
LAKLPNADKPIVTEPGDAVATLNSLVIEMENRYKLLVEASARNIKEYNEKFISRRLNPEK
GHRFLPYIVAIVDEFADLIATSGKEIELPISRIAAKARAVGIHMILATQRPDTKVITGTI
KSNFPSRIAFKVMSQIDSRTILDTPGANRLIGKGDMLVLITGSSEPTRVQCAFVDTPEVE
DIVNYVGAQVAYPTAYLLPEYIGEGGESSSAGTVDLSDRDPLFDEAARLIVIQQQGSTSL
IQRKFAIGYNRAGRLMDQLEAAGIVGPFEGSKARQVLIQDEYSLEQLLNSLK