Protein Info for HMPREF1078_RS13605 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1107 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 115 to 1107 (993 residues), 884 bits, see alignment E=1.8e-269 PF13620: CarboxypepD_reg" amino acids 116 to 187 (72 residues), 46 bits, see alignment 8.2e-16 PF13715: CarbopepD_reg_2" amino acids 117 to 198 (82 residues), 76 bits, see alignment 2.9e-25 PF07715: Plug" amino acids 205 to 313 (109 residues), 73.1 bits, see alignment E=3.9e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 289 to 319 (31 residues), 63.6 bits, see alignment (E = 1.1e-21)

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1107 amino acids)

>HMPREF1078_RS13605 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MKIIIILLVLSIGNSFSMTYSQNTLLSLDINKQSIKEVIGIIEKKSEYVFFFSDNVRQDL
EKSVDIKVNSKTLDVILNNLFADTDLVYTINDRQVSIAKSKKAGSSYPAPQQQTKTITGT
IVDNTKEPLIGVNIVVKGTSTGTVTDIDGKFSLPITETNAVLVISYIGYKSQEIKVGNQS
SLNVTLEAETLGLEEIVVVGYGTVKKKDLTGSVSSVNSETISKSPVTSATQAIQGHLPGV
FISNSTTKPGENASVVIRGKRSISGSSDPLYIVDGIPVVGGINEISPSDIETIDILKDAS
ATAIYGARGSNGVILITTKRGKAGKTQVDYNGYVGFQTVLNQLEYMDGAAYAETVRESYR
STGKYLSDKPSWEEDQKIGSFANDPYTLESLKMAYDENGNYDPSKVRSGSKWWEAVQRTG
MVTDHQLSVRGGNDKTNFTFSGSYYDYKGLVKDEEFSRYSIRLNLEHSVNKYIKLGAFTG
YTHSVQERGSTLFNSWRVMPMGRFYDDNGDLLEKVSGTDDQWRNPLLRLAEGAVSNPLKI
NRFIGSYYADITLPLKGLRFRTNLGIDYETRQDYNFQSAEARGNTMNYARNGTENRSMFT
WENLLFYDRTFEDHTIGVTLLQSINEYLREYNKIPVQGTPADELLYYDVGSASNPEKTES
GKSQWKLASFMARLNYSFKGKYLATISARYDGSSRLAEGHQWVAFPAAALAWRINEESFM
QNVHFLSNLKLRVGYGVVASSEVDPYETKGTLSQKPYNYGSESIFGYAPDKMPNTMLTWE
TTGQWNAGFDFGFLGNRLNGTIDVYLQNTKDLLLDRQLPIVSGFNQIKSNVGKTRNKGLE
LTLNSLNINNKNFTWSTDLMMYTNKEEIVELYNGKEDDPGSSWFIGEAINVFYDYKKIGI
WQDTPEDRAEMEKFNQNGSNFAPGTIRLWDNGDYKITSEDRVIQGQQRPKVILSLNNTFR
YRDFDFSFFFEGNFGAMIKNNISYLNQAHRNGNVKVDYWTPTNPTNAFPRPIEGVDYLPY
YETLHYEKSDFIKLRNVTLGYTIPSHITKKWDISRCRVYVQAQNSWMWTNFTGVDPESAL
NKDVDGTYAGYTRPTPSTWLVGLNISF