Protein Info for HMPREF1078_RS12725 in Parabacteroides merdae CL09T00C40

Annotation: DUF349 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 637 PF03993: DUF349" amino acids 137 to 208 (72 residues), 51.8 bits, see alignment E=4.1e-18 amino acids 212 to 285 (74 residues), 63.6 bits, see alignment E=8.8e-22 amino acids 289 to 367 (79 residues), 77.3 bits, see alignment E=4.7e-26 amino acids 372 to 444 (73 residues), 91 bits, see alignment E=2.5e-30 amino acids 448 to 520 (73 residues), 74.6 bits, see alignment E=3.2e-25

Best Hits

KEGG orthology group: None (inferred from 80% identity to pdi:BDI_2685)

Predicted SEED Role

"FIG00896368: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (637 amino acids)

>HMPREF1078_RS12725 DUF349 domain-containing protein (Parabacteroides merdae CL09T00C40)
MKDTHEANLPTEENGKLEETKAPETTPENTAEEVVTNETTDAEVAAEETSEAEVKTDEVA
AGEETVATTGKLSKEEILEKLTGLVGAAADATRNEVEALKQAYYKIHRSEVDELKKAFLT
AGGEEKDFVAPEDETESKIKELLNVYKEKRAAILAEEERVKAANYALKLQLIDQLKALTE
SQEDFNKLYNDFKDIQQRWKEVKAVPQEHVSELWKNYQTYSEMFYDIIKINNQFRDYDFK
KNLEMKTALCETVEKLQTEPDVISAFHQLQKLHQQWREIGPVAKELREDLWSRFKAASTI
INKRHQEHFEGLKAKEQENLEAKTAICEQIENIDFPALKSFKDWEEKNKEVIALQDKWKT
IGFAPKKSNVKIFERFRAACDVYFNRKSEFYKNIKDEMEKNLALKKALCEKAEALKDSTD
WKSTTEKMIALQKEWKTIGSVARKHSDAVWKRFITACDYFFEQKNKNVSSQKSVEQTNLA
AKKALIEKINTIDEADHDEALATLKGYMTEWNAIGHVPFKEKDKIYKEYHEAVDKQFDRL
KVDQNDRKMQTFRNSLSDMSNGERGKGKLYGEREKLMRMYERMKNELQTYENNIGFLSIS
SKGGGGLLKEMERKIDKLKDEMALIIKKIDAIDENLE