Protein Info for HMPREF1078_RS12520 in Parabacteroides merdae CL09T00C40

Annotation: F0F1 ATP synthase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 526 TIGR00962: ATP synthase F1, alpha subunit" amino acids 4 to 523 (520 residues), 761 bits, see alignment E=2.9e-233 PF02874: ATP-synt_ab_N" amino acids 27 to 94 (68 residues), 58 bits, see alignment E=1.7e-19 PF00006: ATP-synt_ab" amino acids 152 to 390 (239 residues), 263.7 bits, see alignment E=1.9e-82 PF00306: ATP-synt_ab_C" amino acids 397 to 521 (125 residues), 138.9 bits, see alignment E=1.7e-44

Best Hits

Swiss-Prot: 94% identical to ATPA_PARD8: ATP synthase subunit alpha (atpA) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

KEGG orthology group: K02111, F-type H+-transporting ATPase subunit alpha [EC: 3.6.3.14] (inferred from 94% identity to pdi:BDI_0264)

Predicted SEED Role

"ATP synthase alpha chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (526 amino acids)

>HMPREF1078_RS12520 F0F1 ATP synthase subunit alpha (Parabacteroides merdae CL09T00C40)
MTDQIKVSEVSAILRQQLEGISTGIRTEEVGTVLQVSDGVARIYGLDNAEANELLQFDNG
MEAIVMNLEEDNVGAVLLGPTDQVKEGDIVKRTGRIASINVSEGMIGRVIDPLGNPIDGK
GEITGEACEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMIPIGRGQRELIIGDRQTGKTS
IAIDTIINQRGNYEAGNPVYCIYVAIGQKGSTVASLVNTLQEKGAMDYTIIVSATASDPA
AMQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFY
LHSRLLERAAKIINQPEVARQMNDLPDSMKDKVKGGGSLTALPIIETQAGDVSAYIPTNV
ISITDGQIFLETDLFNQGNRPAINVGISVSRVGGNAQLKAMKKVAGTLKIDQAQFRELES
FSKFGGEMDAVTAFTIDKGQKNTQLLIQPQYSPMPVEDQIAILYCGTQGLLKGVPLDKVH
DFEKEFLHELHTSHQHDVLDILKTGTINDDIRKKLEETAKQLTMNN