Protein Info for HMPREF1078_RS12515 in Parabacteroides merdae CL09T00C40

Annotation: F0F1 ATP synthase subunit delta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 180 TIGR01145: ATP synthase F1, delta subunit" amino acids 6 to 176 (171 residues), 90.5 bits, see alignment E=7.8e-30 PF00213: OSCP" amino acids 6 to 176 (171 residues), 124.2 bits, see alignment E=3.1e-40

Best Hits

Swiss-Prot: 78% identical to ATPD_PARD8: ATP synthase subunit delta (atpH) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

KEGG orthology group: K02113, F-type H+-transporting ATPase subunit delta [EC: 3.6.3.14] (inferred from 78% identity to pdi:BDI_0265)

MetaCyc: 32% identical to ATP synthase F1, delta subunit (Synechococcus elongatus PCC 7942 = FACHB-805)
ATPSYN-RXN [EC: 7.1.2.2]

Predicted SEED Role

"ATP synthase delta chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14 or 7.1.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (180 amino acids)

>HMPREF1078_RS12515 F0F1 ATP synthase subunit delta (Parabacteroides merdae CL09T00C40)
MDIGTISSRYAKALFSLAKEKGLETRVYDDMKMLADSFSLEPGLRVALGNPILPAEEKLK
LLTAAGGIEVSDLYERFMHLVLEHKRESLLLFMAHIYIHLYRKDKRITRVQFSTAVPVSE
EVKVHLQNKLKEETGSTIEFSGIVQPELIGGFRLRIGNYRIDASYATQLRDIRSRLLENR