Protein Info for HMPREF1078_RS12480 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF07715: Plug" amino acids 53 to 142 (90 residues), 44.8 bits, see alignment E=2.4e-15 PF00593: TonB_dep_Rec" amino acids 231 to 638 (408 residues), 115.7 bits, see alignment E=7.9e-37 PF14905: OMP_b-brl_3" amino acids 413 to 635 (223 residues), 34.9 bits, see alignment E=1.5e-12

Best Hits

KEGG orthology group: None (inferred from 62% identity to pdi:BDI_3417)

Predicted SEED Role

"Outer membrane vitamin B12 receptor BtuB" in subsystem Coenzyme B12 biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (665 amino acids)

>HMPREF1078_RS12480 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MQNIFVKRLSGLLCAWLFPFAALYAQVDTTTYHQLSGVEVLGKVRPSTTRESTPLQVMDK
AGIERLGVQDLSEAVKRFSGVTVQDYGGIGGLKTVSVRSLGAKHTAVCYDGVTVTDAQSG
QVDISRFSLDNVDMISLSIGQADDIFQTARMYASAGALSIKTSRPVFTDRSYHLKAQVKA
GSFGLVNPYLRYEQKLGKKWYTSWHGDYLRADGNYPFTLVNGNLIEKKKRYNSDIESWRT
ELNFTGDLGKFGTLSMKGYYFDSHRGLPGSVIFYNDYSGERLWDRNAFAQIHYENHITEK
FTFQAQAKYNYSWMRHLDVDNKYESGRQDDRYTQKEYYLSISGLYSLADHLSLAVAEDYF
INSLDNTIPECPFPKRYTSLTALAIQYKDPRLTATTSLLGTYITENVERGDRPSDRKRLS
PAVSLSWRVLSDHNFRLRASYKDIFRVPTFNDLYYLRIGNTDLKPERATQYNVGMTWSGL
LPFINYLNVSVDGYYNRVSDKIVAIPTMFIWKMMNMGEVSIGGIDVNLSTEVPLWKNISL
TGQMSYSWQHAIDITDETEKNYRDQIPYTPKHSGNFSAALQMPWINISYLLTVVGDRYAS
PQNIERNLIDRYAEQTVSLNRTFTFGSCSLRLQFDIINIGNINYDVVKYYPMPGRSFRGG
LVFIY