Protein Info for HMPREF1078_RS11870 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1096 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF07660: STN" amino acids 49 to 99 (51 residues), 45.9 bits, see alignment 9.4e-16 TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 114 to 1096 (983 residues), 938.6 bits, see alignment E=5.5e-286 PF13715: CarbopepD_reg_2" amino acids 114 to 194 (81 residues), 67.9 bits, see alignment 1.6e-22 PF13620: CarboxypepD_reg" amino acids 114 to 182 (69 residues), 39.2 bits, see alignment 1.9e-13 PF07715: Plug" amino acids 202 to 307 (106 residues), 73.8 bits, see alignment E=4e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 283 to 313 (31 residues), 62.4 bits, see alignment (E = 2.5e-21) PF00593: TonB_dep_Rec" amino acids 472 to 1054 (583 residues), 53.6 bits, see alignment E=9.2e-18

Best Hits

KEGG orthology group: None (inferred from 71% identity to bvu:BVU_0389)

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1096 amino acids)

>HMPREF1078_RS11870 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MRISTFLLGACVFCSYAEDSHSQNARVSINKNNSQLEEILNEIESQTDYLFIYNNQVDVN
RKVSVKAKTKPVSEVLDNLFKNAGIEYEMEGTHIILSSKSRDAIAAAQQQTHVLTGRIVD
NNGEAIIGANVVVKGTTNGTVTDIDGNFSIEADPNSVLNISYIGYLSKEIVVGNQKTINV
VLLEDTKTLDEVVVIGYGTQKKADLTGSVANVSTDDLNTQSNTTIGQALQGKIAGVDIVS
QGGAPGGSTRVMVRGIGTLNNSSPLYIVDGMYMSGIDHINPNDIASIDVLKDASSAAIYG
SRAANGVVIVTTKEGSNTEGKPIIDLSANVGVSSPSKYLDLLDAAGWAEVTTVSRRAAGL
SPLEMAQDLASKPDNDWQDLMFGPALMQNYALSVKGGGKYSTYYNSVGYTNQDGVMKGTN
YQRYTLQSKQDFKKGIFQAGTNVVLTYDQSNPLYSVIRGGMVGHTLQAIPTWEQYDENRT
GGYGGLYGDVVNLTHPLGMVDDNLMKRYSDNVKIFANAYVSVELMKGLKYKLNLTPDFQF
YRYNSYEGLFDFGLAKHDITAVTEQQTRTRNILVENLLTFDRTFGDHKVSALVGYTYQDS
RYRYMQGSGQGMPTGITEIDAASQGLAVSGNSSRSVLTSILGRAFYSYKNRYLLTATIRR
DGSSKFGSNYRYGNFPSVSVGWNIAEEDFVKNSVSWLDQLKLRGGYGVLGNQEIDNYQYV
SVVTTGINYPDGKSGLIQGAFPKTFANPDIKWEETAMTNVGIDFMALRNRLTLTADWYVK
NTKDILLNVPIPISTGGANDPIRNAGKIRNQGFEFNLGWNESLNKDLSYGVSFLGTYNKN
EVVEMGAESQVITGGTIHGGTYTSRTLAGYPIGGFWLIPTDGYFNSTEEVQAHQKDGVLI
QPSAEPGDIRFKDTNNDGTINDEDRVYCGSPFPKFTYSINGNITYKNVDFSIGFQGVTGN
KIYNATKLELTDVTRGTNYLASTLDYWTPENQNASSPRLIWTDPNRNARSESDRYLESGS
YFRLRNLQVGYTLPTVWFHGFVQKARVYVNAENLFTISSYSGYTPDVNSSDVYSRGFDEF
IYPSNRTFMFGLNVTF