Protein Info for HMPREF1078_RS11005 in Parabacteroides merdae CL09T00C40

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 999 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13525: YfiO" amino acids 28 to 114 (87 residues), 35.6 bits, see alignment E=5.9e-12 amino acids 618 to 691 (74 residues), 31 bits, see alignment 1.5e-10 PF12895: ANAPC3" amino acids 260 to 339 (80 residues), 32.6 bits, see alignment E=5.5e-11 PF13181: TPR_8" amino acids 316 to 342 (27 residues), 15 bits, see alignment (E = 1.6e-05) amino acids 467 to 493 (27 residues), 15.9 bits, see alignment (E = 8e-06) amino acids 507 to 537 (31 residues), 15.2 bits, see alignment (E = 1.4e-05) amino acids 544 to 575 (32 residues), 13 bits, see alignment (E = 7e-05) amino acids 658 to 684 (27 residues), 12.1 bits, see alignment (E = 0.00014) PF13174: TPR_6" amino acids 316 to 340 (25 residues), 17.6 bits, see alignment (E = 3.4e-06) amino acids 467 to 495 (29 residues), 19.4 bits, see alignment (E = 8.8e-07) amino acids 507 to 533 (27 residues), 15.5 bits, see alignment (E = 1.6e-05) amino acids 581 to 612 (32 residues), 13.4 bits, see alignment (E = 7.4e-05) amino acids 617 to 649 (33 residues), 18.9 bits, see alignment (E = 1.3e-06) amino acids 658 to 686 (29 residues), 23.8 bits, see alignment (E = 3.6e-08) amino acids 956 to 980 (25 residues), 14.7 bits, see alignment (E = 2.7e-05) PF13432: TPR_16" amino acids 433 to 493 (61 residues), 19.8 bits, see alignment 6.5e-07 amino acids 509 to 577 (69 residues), 26.4 bits, see alignment 5.7e-09 amino acids 741 to 792 (52 residues), 23.6 bits, see alignment 4.3e-08

Best Hits

KEGG orthology group: None (inferred from 82% identity to pdi:BDI_3591)

Predicted SEED Role

"TPR-domain containing protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (999 amino acids)

>HMPREF1078_RS11005 tetratricopeptide repeat protein (Parabacteroides merdae CL09T00C40)
MKRILIPLCIVVGSHVAYGQRSYQFDAPDRLFVEGKELFSLKNYAGCIDKLEAYKQHSTN
ADLIQEADYMLVYAAYEQGRPNADELLKDYLEEYPASRHSDEIGYMIGSVHFKRGEYEKA
IFWFNEADIDMLSPEQQEAYSFRLAYSLLQTGEMEKARGYFARIEQVGDKYKEASTYYVA
YIDYAMGNYNNALIEFSRLKESPKYREQSQYYIAQIYFIQSKYEKVVKEGEELLSLYPDS
KNNSEMYRIVGDSYYHLGDQEKAIRMLSKYVSSTENPLRSDLYILGVCYFNKGNYSNTVN
ALSRTVRQNDELTQNAYLYLGQSYLKLGDKNNARMAFEAAATSSFDKQIKEVAMYNYALL
IHETAFTGFGESVTIFEDFLNDFPNSQYADKVNDYLVEVYLTTKNYEAALKSINKIKHPS
TKILEAKQDILFQLGTQAFANVKLDDAVSLFSQAIQLGSYNMEARNDAYFWRGESYYRMG
EYENAISDYRTYLNNTRQRNTDMYALAYYNLGYSYFKLRDYSAALNRFRQYVDLESNRQA
ASLADAYNRIGDCLYQNRQFSLAEENYSRAAQLSPSAGDYSIYQKGFLLGLQKDYKGKIS
AMDRLISEYPESQYVDDALFEKGRSYVLLENSSSAAQAFEKLIREFPLSSLARKAGIQLG
LLYYNDNQPEKALAAYKQVISNYPGSEEAKIALQDLKSVYIDLNDINAYASYVNSIGGNI
RLEVGEQDSLTYIAAEKLFMRGDNDGARRSLINYLQTFPEGAFSSNANFYLGSIAFAKKE
FDEAIQRFKSVIASGDTKFLEESVARTAEIEYLSKDYPAALESFKRLQIVAENPENRQAA
RLGIMRCALQTGQQKDALLAADELLKEPKLSPELEAEARYVRAKAYIAQKQANKALADLK
ELSKDTRTVHGAEAKYLLAQLYYDTNDDKNAEKVLMNFIENGTPHQYWLARGFILLADIY
IRQGDDFQARQYLTSLQNNYKGDDDIAGMIENRLGKLKN