Protein Info for HMPREF1078_RS10700 in Parabacteroides merdae CL09T00C40

Annotation: MarC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details amino acids 75 to 94 (20 residues), see Phobius details amino acids 113 to 136 (24 residues), see Phobius details amino acids 142 to 163 (22 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details TIGR00427: membrane protein, MarC family" amino acids 4 to 200 (197 residues), 193.8 bits, see alignment E=1.4e-61 PF01914: MarC" amino acids 6 to 204 (199 residues), 199.3 bits, see alignment E=2.4e-63

Best Hits

Swiss-Prot: 36% identical to Y1677_METJA: UPF0056 membrane protein MJ1677 (MJ1677) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 84% identity to pdi:BDI_0008)

Predicted SEED Role

"MarC family integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (214 amino acids)

>HMPREF1078_RS10700 MarC family protein (Parabacteroides merdae CL09T00C40)
MDSLLPFFLLCFTSFFTLTNPLGTMPVFLTMTNGMSEEQRRAIVRRATIVSFLTLMVFTF
SGQFLFKFFGISTNGFRIAGGIIIFTIGFDMLQARYAKAKLKEEEVKTYVNDISITPLAI
PMLCGPGAIANALMLMDDAVTLAKKCILIGTIGLIYFITYLILRASTRLNRYMGETGNNV
MMRLMGLILMVIAVECFVSGFKPIMIDILQHSNL