Protein Info for HMPREF1078_RS10585 in Parabacteroides merdae CL09T00C40

Annotation: aspartate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 11 to 373 (363 residues), 339.7 bits, E=2.1e-105
• PF00155: Aminotran_1_2
  • amino acids 47 to 247 (201 residues), 19.8 bits, E=3.9e-08

Best Hits

KEGG orthology group: K00818, acetylornithine aminotransferase [EC: 2.6.1.11] (inferred from 94% identity to pdi:BDI_0067)

Predicted SEED Role

"Acetylornithine aminotransferase (EC 2.6.1.11)" in subsystem Arginine Biosynthesis extended (EC 2.6.1.11)

MetaCyc Pathways

• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (9/9 steps found)
• L-arginine biosynthesis I (via L-ornithine) (8/9 steps found)
• L-ornithine biosynthesis I (5/5 steps found)
• L-arginine biosynthesis II (acetyl cycle) (8/10 steps found)
• superpathway of arginine and polyamine biosynthesis (10/17 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Lysine biosynthesis
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.11

Protein Sequence (375 amino acids)

>HMPREF1078_RS10585 aspartate aminotransferase family protein (Parabacteroides merdae CL09T00C40)
MNLFDVYPLFNIEIVKGKGCHVWDTEGNEYLDLYGGHAVISVGHSHPTYVKAITEQVNKL
GFYSNSVINSLQQKLADKLGKASGYDDYSLFLINSGAEANENALKLASFHNGKKRVIAFK
HAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDATAVEAELQKGDVSSVIIEGIQGV
GGIQLPTDSFMQELRALCTKYEACLILDEIQSGYGRSGKFFAHQYAGIKPDLISVAKGIG
NGFPMSGLLISPMFKPVYGMLGTTFGGNHLACAAAIAVLEIMEEEKLIDNAREVGAYLLD
ELHKLPGIKEIRGRGLMIGIEFEESIKEVRSKLLFEEKVFTGVAGTNTIRLLPPLCLSMD
EAKEFIVRFRKVLNA