Protein Info for HMPREF1078_RS10315 in Parabacteroides merdae CL09T00C40

Annotation: calcium/sodium antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 38 to 55 (18 residues), see Phobius details amino acids 69 to 92 (24 residues), see Phobius details amino acids 103 to 123 (21 residues), see Phobius details amino acids 129 to 146 (18 residues), see Phobius details amino acids 166 to 187 (22 residues), see Phobius details amino acids 203 to 227 (25 residues), see Phobius details amino acids 235 to 258 (24 residues), see Phobius details amino acids 264 to 282 (19 residues), see Phobius details amino acids 294 to 310 (17 residues), see Phobius details TIGR00367: K+-dependent Na+/Ca+ exchanger homolog" amino acids 3 to 304 (302 residues), 273.5 bits, see alignment E=1.1e-85 PF01699: Na_Ca_ex" amino acids 4 to 144 (141 residues), 115.1 bits, see alignment E=1.4e-37 amino acids 171 to 309 (139 residues), 122.6 bits, see alignment E=6.9e-40

Best Hits

KEGG orthology group: K07301, inner membrane protein (inferred from 51% identity to sse:Ssed_0330)

Predicted SEED Role

"Inner membrane protein YrbG, predicted calcium/sodium:proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (313 amino acids)

>HMPREF1078_RS10315 calcium/sodium antiporter (Parabacteroides merdae CL09T00C40)
MITSLTLLILSLVALYIGAGWLVQGSSALALKAKISPLVVGLTIVAFGTSAPELVVSLNA
TLSGQGDIAIGNIVGSNIFNIGVILGVSATICPLQVKKQLLRIDIPVMLAATVLFTILFW
NGTLGRTEGLFFLTGIIIYTIFSLFYSRKHGTEGSSQELEEQPKHWAVDTLAIVGGLVVL
VFASRLLVDNAVSIAKELGVSEAVIGLTIVAAGTSMPELATSIVAAYKRKTDIAIGNIVG
SNLFNILTIAGSCSLIHPIEAKNVNYIDLLVMLGISVLLLPLVKSGQKISRTEGFVLILF
YVIYMFWLLRDTL