Protein Info for HMPREF1078_RS09890 in Parabacteroides merdae CL09T00C40

Annotation: cation:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 771 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 65 to 86 (22 residues), see Phobius details amino acids 97 to 122 (26 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 196 to 217 (22 residues), see Phobius details amino acids 231 to 256 (26 residues), see Phobius details amino acids 262 to 284 (23 residues), see Phobius details amino acids 296 to 315 (20 residues), see Phobius details amino acids 321 to 338 (18 residues), see Phobius details amino acids 350 to 366 (17 residues), see Phobius details amino acids 378 to 400 (23 residues), see Phobius details amino acids 412 to 432 (21 residues), see Phobius details amino acids 442 to 466 (25 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 79 to 458 (380 residues), 212.4 bits, see alignment E=5e-67

Best Hits

KEGG orthology group: None (inferred from 82% identity to pdi:BDI_1727)

Predicted SEED Role

"Na(+)/H(+) antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (771 amino acids)

>HMPREF1078_RS09890 cation:proton antiporter (Parabacteroides merdae CL09T00C40)
MGKGTKSIAFYLMMILVFGSLMYFIVKEGESQQVGTAVQTMQNAPQTMGEGFLVFWDSVT
HHIQSSMGILLLQIITILIVCRLFGWMFQKIGQPTVIGEIVAGIVLGPSVLGHLLPGVSA
FLFPLESLGNITILSQFGLILFMFAIGMELDIGEVRKKLKETILISHTSTIVPFFFGMLT
AYYVYGSYAHKGTPFLSFALFIGIAMSITAFPVLARIIQEKGLTKTHLGTISLASAANGD
ITAWCLLAVVIAIAQAGSMLSAVYNILFSILYILFMFLAVRPFLRMIGHIYHNKEVIDKA
LVALMFLLLIVSSYFTEILGLHALFGAFIAGVVMPGNIKFRKIMTEKVEDVSLALFLPLF
FVSTGLRTEIGLLNTPELWVMCGIFIVVAIIGKFGGALFSARFVGESWKDSFYIGALMNT
RGLMELVVLTIGYEMKILPPSIFVMLVLMTLVTTFMTIPLVSFIKLCFKTREKIKEHQVC
VEPADGIFKVLLSFGRAGNGQIMLDVAHQMFARGKNKLDLTALHLTVGSDVNPLHTDNFE
EVSFGPILYGAKKLGMHIHTRYEVSNNAGQDICDIVNNEGFDFLLVGSGISMSDSPDDIA
ATRYRTSFYNRYFKRFKAPESWFYPGALLKDKTKMFIARSNCDVGVFINRNFVKATNTLV
VISSEEDLFLLDYTRTLLKATHGSVGIVAKMSTTTPGHDQILKELWDFVSSIPQTQLLPD
KDLTPGLFNSYNFMLIGYNTWNDVSEHRKEALQKMPSTLILNKNKRSSSDN