Protein Info for HMPREF1078_RS09885 in Parabacteroides merdae CL09T00C40

Annotation: alpha amylase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02922: CBM_48
  • amino acids 52 to 118 (67 residues), 38.7 bits, E=1.6e-13
• PF00128: Alpha-amylase
  • amino acids 201 to 266 (66 residues), 39.2 bits, E=1e-13
• PF02806: Alpha-amylase_C
  • amino acids 575 to 667 (93 residues), 67.8 bits, E=1.3e-22

Best Hits

KEGG orthology group: K00700, 1,4-alpha-glucan branching enzyme [EC: 2.4.1.18] (inferred from 90% identity to pdi:BDI_1726)

Predicted SEED Role

"1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)" in subsystem Glycogen metabolism or Trehalose Biosynthesis (EC 2.4.1.18)

MetaCyc Pathways

• glycogen biosynthesis I (from ADP-D-Glucose) (3/4 steps found)
• glycogen biosynthesis II (from UDP-D-Glucose) (1/4 steps found)
• starch biosynthesis (5/10 steps found)
• glycogen biosynthesis III (from α-maltose 1-phosphate) (2/8 steps found)

KEGG Metabolic Maps

• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.18

Protein Sequence (672 amino acids)

>HMPREF1078_RS09885 alpha amylase C-terminal domain-containing protein (Parabacteroides merdae CL09T00C40)
MESLNLIKNDPWLAPYKEAIEGRYQYVVNKEKNLTGNGRQTLSEMASGYLYFGLHKTKSG
WVFREWAPNATAIYMIGTFNEWKKDDRYKLQRLGNGIWEIALAEGLLRHEDLFKLLVEWE
GGCGERIPAWIRRVVQDENTKIFSAQVWNPEKPYVFKHKRFKPNVSPLLIYECHIGMASN
EEKVGSYDEFRRMVLPRIAKEGYNAIQIMAIQEHPYYGSFGYHVSSFFAASSRFGTPEEL
KQLIDEAHSMGIAVIMDIVHSHAVKNEVEGLGRFDGSYTQYFLGGARREHPAWDSLCFDY
GKNEVLHFLLSNCKFWLDEYKFDGFRFDGVTSMLYYSHGLGEAFCNYADYFNGHQDGDAI
AYLTLANKLIHEVNKNAITIAEEVSGMPGLAAKYEDGGYGFDYRMAMNIPDYWIKTIKEK
KDEDWHPSSIWWETTNRRADEKTISYAESHDQALVGDKTIIFRLIDADMYWHMQKDDHNF
MVERGVALHKMIRLVTASTINGGYLNFMGNEFGHPEWIDFPREGNGWSHKYARRQWDLVD
NMDLKYHFLGDFDREMLELIRSVKNFQSTPIQKVWDNDGDQILAYMRKDLVFVFNFNPTK
SFADYGFLVPKGEYEVVLNTDANRFGGFGLADDTIHHFTQFDPLYKKEKKEWLKLYIPAR
SAVVLKKVKKAK