Protein Info for HMPREF1078_RS09735 in Parabacteroides merdae CL09T00C40

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 38 to 56 (19 residues), see Phobius details amino acids 68 to 88 (21 residues), see Phobius details amino acids 95 to 115 (21 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 178 to 198 (21 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 243 to 262 (20 residues), see Phobius details amino acids 273 to 295 (23 residues), see Phobius details PF00892: EamA" amino acids 6 to 139 (134 residues), 62.9 bits, see alignment E=2e-21 amino acids 150 to 285 (136 residues), 64.5 bits, see alignment E=6.6e-22

Best Hits

KEGG orthology group: None (inferred from 82% identity to pdi:BDI_3450)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>HMPREF1078_RS09735 DMT family transporter (Parabacteroides merdae CL09T00C40)
MNTKVKGYFLGAIAAATYGTNPLFALPLYKDGMDPDSVLFFRYLFAIPILGMMIKGRGRS
FKIEHKAAVPLIVMGLLVAFSSLALFQSYNYMEVGIASTLLFVYPIMVALIMALVFKEKL
TLQTVFCILLALSGIGLLYKSGDGTTLSLTGVLLVMASALSYAIYIIGVNQSTLKNVATL
PLTFYILLFGVSLFFVRVGFGKDLYIVDKWYLWGNLIALAVFPTAISFLCTTSAVQYIGS
TPTAILGALEPVTAVFFGVAVFGETLTPRIGCGILLIILAVTIIIAGSNITSHLIRFRKL
FPRLPLKRKGKMNG