Protein Info for HMPREF1078_RS09720 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF07715: Plug" amino acids 46 to 159 (114 residues), 74.3 bits, see alignment E=1.1e-24 PF00593: TonB_dep_Rec_b-barrel" amino acids 216 to 601 (386 residues), 152.5 bits, see alignment E=3.4e-48

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 77% identity to pdi:BDI_0605)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (627 amino acids)

>HMPREF1078_RS09720 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MKKVILLASGLLCSSLVFASDPAAIDSLINLQGVVISANKVQVNRSSVPLTISVIDREQI
EASSESALLPVLSQHVPGLFVTQKGITGFGVSEGAAGTVNIRGVGSGNKVLMLFDGQPQW
AGVFGHSLPDTYVASDVERVEVIRGPGSLLYGSNAMGGVVNIITRHHKQKGRRTQARVMY
GSYNTQKYMVNNGFNVGKFSSFISINHDRTDGHRPNSDFNITNGFANLGYAFNEHYKMTG
DVSLAKSKFQNPGKTFEPVIDNKMNILRGTASMALENNQGKMSGALRLFYNWGNHKINDG
YNPGEEPLTYLFRSDDHNVGVQLYESFRLFKGNNFTVGVDYKNWGGHAWNDNNDGSKKEL
VDKTVNETAGYAIMQQELFGILSLNAGVRYEHSSTYGGEWVPQGGVTVRPFEGNTIRASV
SKGFRSPNIREMYMWGAANADLKPESMVNYEVAVGQSFLGGDLYTELTAFFIDGKDMIYS
VSVNGDGRPPYKNLNTGTFTNKGIEFEARYQICKNLNLDMNYSYLHMSKPIPGAPGHKFY
AGATYMPGRFTLNVNMQSVFDLYTDAEYSKKEDFTTLNAKVAYRFGTRDKGLNLFVKGEN
LTATRYTINDGFPMPKAIFMGGIDVTF