Protein Info for HMPREF1078_RS09465 in Parabacteroides merdae CL09T00C40

Annotation: 4Fe-4S binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 40 to 61 (22 residues), see Phobius details amino acids 67 to 79 (13 residues), see Phobius details amino acids 100 to 126 (27 residues), see Phobius details amino acids 167 to 189 (23 residues), see Phobius details amino acids 196 to 214 (19 residues), see Phobius details PF12801: Fer4_5" amino acids 49 to 89 (41 residues), 48.1 bits, see alignment 4.1e-16 amino acids 179 to 216 (38 residues), 29 bits, see alignment 3.7e-10 PF12838: Fer4_7" amino acids 436 to 484 (49 residues), 36 bits, see alignment 3.5e-12 PF00037: Fer4" amino acids 465 to 484 (20 residues), 30.5 bits, see alignment (E = 1e-10) PF12797: Fer4_2" amino acids 465 to 484 (20 residues), 26.6 bits, see alignment (E = 1.7e-09) PF12837: Fer4_6" amino acids 465 to 484 (20 residues), 25.9 bits, see alignment (E = 3.3e-09)

Best Hits

KEGG orthology group: None (inferred from 69% identity to pdi:BDI_0395)

Predicted SEED Role

"Ferredoxin-type protein NapG (periplasmic nitrate reductase)" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>HMPREF1078_RS09465 4Fe-4S binding protein (Parabacteroides merdae CL09T00C40)
MLRTIRLTTALICFTLVTLLFLDFTGTLHAWFGWLAKVQFLPAVLALNLGVVLFLIVLTW
IFGRVYCSVICPLGIFQDVVSWLAGKRKKNRFRYSPALSWLRYGAMVIFILAMISGLGAW
AALIAPYSAYGRIASNLFAPLWQWGNNFLAYLAERADNYAFYETEVWLRSLPTFIIATVT
FIILIILAWRNGRTYCNTICPVGTFLGLISRFSVFKPVIDTSKCNGCGLCARNCKAACIN
AKVHEIDYSRCVDCMDCIDKCRQGAIRYTRRKTNKAETQTNQPVVDKPDRRKFFTVSALL
ATSATLKAQEKVQLPDKKVDGGLAIIEDKKKPDRTTPITPPGSLSAANFSQHCTACQLCV
SVCTNHVLRPSGNLQTFMQPEVSYERGYCRPECVKCSEVCPTGAIRPITKADKTAIQIGH
AVLIQENCIVNRDGVTCGNCARHCPTQAILMVAKDPNDPDSPQLPVVNEEKCIGCGACEN
LCPSRPFSAIYVEGHEQHRNI