Protein Info for HMPREF1078_RS09445 in Parabacteroides merdae CL09T00C40

Annotation: peptide-methionine (R)-S-oxide reductase MsrB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 PF01625: PMSR" amino acids 13 to 169 (157 residues), 211.6 bits, see alignment E=8.4e-67 TIGR00401: peptide-methionine (S)-S-oxide reductase" amino acids 13 to 162 (150 residues), 191.3 bits, see alignment E=1.3e-60 TIGR00357: methionine-R-sulfoxide reductase" amino acids 184 to 317 (134 residues), 209.3 bits, see alignment E=1.8e-66 PF01641: SelR" amino acids 193 to 308 (116 residues), 163.8 bits, see alignment E=1.4e-52

Best Hits

KEGG orthology group: K12267, peptide methionine sulfoxide reductase msrA/msrB [EC: 1.8.4.11 1.8.4.12] (inferred from 78% identity to bth:BT_2499)

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) / Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.11, EC 1.8.4.12)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.11 or 1.8.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>HMPREF1078_RS09445 peptide-methionine (R)-S-oxide reductase MsrB (Parabacteroides merdae CL09T00C40)
MKQENMKMKDKAEIYLAGGCFWGTEHFLKQIRGVEQTEVGYANSQVPNPTYKEVCTGNTG
AVETVKVVYDPRTVDLDLLLDLYFQTIDPTSVNRQGGDSGLQYRTGIYYIDKDDAPVIEA
AIKDLAKDYAKPIAIEVMPLVNFYAAEEYHQDYLDKNVGGYCHINPKLFELARKANARPV
YAKPDDVTLKNKLSDIQYAVTQKNATEPAFRNEYWNEHREGIYVDITTGEPLFVSTDKFD
SGCGWPSFSKPIDKKLIVEKPDTSHGMTRTEVRSQTGNAHLGHVFPDGPADKGGLRYCIN
SASLRFIPKEKMKEEGYGDYLPLLKK