Protein Info for HMPREF1078_RS08780 in Parabacteroides merdae CL09T00C40

Annotation: trimeric intracellular cation channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 transmembrane" amino acids 31 to 51 (21 residues), see Phobius details amino acids 63 to 80 (18 residues), see Phobius details amino acids 90 to 107 (18 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 149 to 169 (21 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details PF03458: Gly_transporter" amino acids 7 to 80 (74 residues), 86.6 bits, see alignment E=4.3e-29 amino acids 92 to 164 (73 residues), 85.3 bits, see alignment E=1.1e-28

Best Hits

Swiss-Prot: 30% identical to Y1240_HAEIN: UPF0126 membrane protein HI_1240 (HI_1240) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 85% identity to pdi:BDI_1706)

Predicted SEED Role

"FIG00896360: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (203 amino acids)

>HMPREF1078_RS08780 trimeric intracellular cation channel family protein (Parabacteroides merdae CL09T00C40)
MIDFITFCDYTGTFAFAISGIRLASAKQFDWFGAYVVGVVTAVGGGTIRDILLNATPFWM
EQASYLIISALALLFVIIFRKYVISLNNTFFIFDAIGLGLFGVVGIEKALTFGFPMWVAI
VMGTITGAFGGMIRDILINEVPLIFRKDIYALACVFGGIIYYACLQMGIGPSLTQLIAAT
GIFVSRIVAVKYHISVPVLKGEE