Protein Info for HMPREF1078_RS08045 in Parabacteroides merdae CL09T00C40
Annotation: L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 84% identical to Y1130_PARD8: UPF0597 protein BDI_1130 (BDI_1130) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
KEGG orthology group: None (inferred from 84% identity to pdi:BDI_1130)Predicted SEED Role
"Putative inner membrane protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (430 amino acids)
>HMPREF1078_RS08045 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha (Parabacteroides merdae CL09T00C40) MDKTTQTQIIKLIHQEVIPAIGCTEPVAVALAAAKAAEVLGCKPEKTEVFLSANILKNAM GVGIPGTGMVGLPIAVALGTLIGKSAYGLEVLRDLTPEALAEGKQVIEDKRIHIALKDNV DKLYIEVICSAGDETSRVIICHEHTNVVYVEKNGVVLTDRRKEGVSCDASGDEDELRLSF STVYEFAMEMPLDEIRFILETADLNRKAAEASLKGNFGHTVSKTVSGVYGRKYMGDSAYT HMLAMTAAACDARMDGAMIPVMSNSGSGNQGIAATLPVLSFAEDIECSEEQLIRALMLSH LMVIYIKQSLGRLSALCGCVVAATGASCGITYLMGGDKVQISYAIKNMIGNITGMICDGA KPSCAMKVSSGVSTAMLSALMAMENKVVTPVEGIIDENVDKSIINLTSIGSKGMEATDKL VLDIMTGKSC