Protein Info for HMPREF1078_RS07895 in Parabacteroides merdae CL09T00C40

Annotation: molecular chaperone DnaJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 PF00226: DnaJ" amino acids 5 to 67 (63 residues), 100.2 bits, see alignment E=8.4e-33 TIGR02349: chaperone protein DnaJ" amino acids 5 to 362 (358 residues), 441.9 bits, see alignment E=1.1e-136 PF01556: DnaJ_C" amino acids 129 to 346 (218 residues), 159.5 bits, see alignment E=9.6e-51 PF00684: DnaJ_CXXCXGXG" amino acids 156 to 220 (65 residues), 66.6 bits, see alignment E=3e-22

Best Hits

Swiss-Prot: 75% identical to DNAJ_BACFN: Chaperone protein DnaJ (dnaJ) from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)

KEGG orthology group: K03686, molecular chaperone DnaJ (inferred from 90% identity to pdi:BDI_1240)

Predicted SEED Role

"Chaperone protein DnaJ" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (385 amino acids)

>HMPREF1078_RS07895 molecular chaperone DnaJ (Parabacteroides merdae CL09T00C40)
MVKRDYYEVLGVEKTASVEEIKKAYRKKAIQYHPDKNPGDKQAEENFKEAAEAYDVLSDP
QKRQRYDQFGHAGVGGASQGGGFGGGMSMDDIFSQFGDIFGGHFGGFGGFGGFGGGSRGG
RRVNRGSDLRVKVKLNLKEIATGVEKKIKVKKYVTCSKCHGSGAEDDHSSKTCETCHGSG
VVTRVANTILGQMQTQTTCPTCGGEGKIITKKCSECNGEGIVRDDEVITINIPAGVAEGM
QLSMSGKGNAARHGGINGDLLILVEEEPHPELIRDENDILYNLLLSVPQAALGGTVEVPT
IDGKAKVKIEPGTQPGKVLRLRNKGLPSVNSYGTGDLLVNVSVYIPETLSASEKDIMNGL
ENSPNFQPKKSVKEKIFDKFRHMFD