Protein Info for HMPREF1078_RS07845 in Parabacteroides merdae CL09T00C40

Annotation: pyruvate:ferredoxin (flavodoxin) oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1182 TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 7 to 1174 (1168 residues), 1936.5 bits, see alignment E=0 PF01855: POR_N" amino acids 24 to 249 (226 residues), 266.1 bits, see alignment E=1.6e-82 PF17147: PFOR_II" amino acids 271 to 376 (106 residues), 59.4 bits, see alignment E=2e-19 PF01558: POR" amino acids 427 to 609 (183 residues), 104.6 bits, see alignment E=3.6e-33 PF10371: EKR" amino acids 628 to 679 (52 residues), 71.3 bits, see alignment (E = 2.3e-23) PF12837: Fer4_6" amino acids 682 to 703 (22 residues), 25.3 bits, see alignment (E = 5.6e-09) PF00037: Fer4" amino acids 683 to 705 (23 residues), 22.5 bits, see alignment (E = 3.8e-08) PF12838: Fer4_7" amino acids 689 to 756 (68 residues), 36.6 bits, see alignment 2.5e-12 PF02775: TPP_enzyme_C" amino acids 961 to 1072 (112 residues), 35 bits, see alignment E=6.2e-12

Best Hits

KEGG orthology group: K03737, putative pyruvate-flavodoxin oxidoreductase [EC: 1.2.7.-] (inferred from 89% identity to bhl:Bache_3115)

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1182 amino acids)

>HMPREF1078_RS07845 pyruvate:ferredoxin (flavodoxin) oxidoreductase (Parabacteroides merdae CL09T00C40)
MTKQKKFLTCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEWAAAGRKNIFGETVMV
QEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAGELLPCVFHVSARTLAS
HALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATIKSRVPFVNFFDGFRTSH
EIQKIEALENEDLAPLIDQKALAEFRARALNPKTPVARGMAENPDHFFQHRESSNSYYDA
VPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSVTEAAREAIDYLTAKGEKVG
LVSVHLYRPFSAKHFLAAVPKTAKRIAVLDRTKEPGAVGEPLYLDVKDCFYGQEDAPVIV
GGRYGLGSKDTTPAQILSVYENLALPMPKNQFTIGIVDDVTFTSLPQKEEIALGGEGMFE
AKFYGLGADGTVGANKNSVKIIGDNTNKYCQAYFSYDSKKSGGFTCSHLRFGDHPIRSTY
LVNTPNFVACHVQAYLRMYDVTRGLRENGTFLLNTVWNGEELAKHLPNRVKRYFAQKNIT
VYYINATQIALEIGLGNRTNTILQSAFFRITGVIPVDLAIEQMKKFIVKSYGKKGEDVVN
KNYAAVDRGGEYNQLTVDPAWANLPDDEEVVNNDPAFINEVVRPINAQDGDLLKVSAFKG
IEDGTWHQGTAKYEKRGVAAFVPVWNEANCIQCNQCAYVCPHASIRPFVLNDEEQKGANF
PMLDVKAPATMKGMKFRMQVDVMDCLGCGNCADICPGFKGNKALSMAPLEGQLAEADNWA
YCVANVSSKQSLVDIKSNVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMVANA
TGCSSIYSGSVPSTPYTTNEKGEGPAWANSLFEDFCEFGLGMELANEKMRARIQNAMEAA
IAYEGTPAEYKEAFTAWIENQNDADKTKELAALIIPMVEAAKDKCPNCATIAELSHFLVK
RSQWIIGGDGASYDIGYGGLDHVIASGKNVNILVLDTEVYSNTGGQSSKATPVGAIAKFA
AAGKRVRKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYDGPSLIIAYAPCINH
GLKKGMGKSQAEEKEAVACGYWHLWRYNPALEAEGKNPFTLDSKEPDWSKFQDFLKGEVR
FASVAKQYPAEAAELFAAAEENAKWRLRSYKRMAAENWSVEE