Protein Info for HMPREF1078_RS07805 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1073 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 42 to 1073 (1032 residues), 916 bits, see alignment E=3.8e-279 PF13620: CarboxypepD_reg" amino acids 43 to 100 (58 residues), 34.7 bits, see alignment 2.8e-12 PF13715: CarbopepD_reg_2" amino acids 43 to 123 (81 residues), 68.5 bits, see alignment 6.3e-23 PF07715: Plug" amino acids 131 to 236 (106 residues), 62.6 bits, see alignment E=7.2e-21 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 212 to 242 (31 residues), 59.2 bits, see alignment (E = 2.6e-20)

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1073 amino acids)

>HMPREF1078_RS07805 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MLKNFKPISLILLAGATCFPASIFAETMPSKQGMNISQQNGKVTGTVVDDLGPVAGASVV
VKGTTNGNITDMDGNFTLEGVKNGDIIQISFIGYTTQEIKYTGQSTLQIKLAEDTQKLEE
VVVVGYGVQKKVNLTGAVGIADSEILEDRPIGNIAQGLQGAIPNLNIDFASGNPNAATTF
NVRGATSLNGGQALLLVDGVETSDLSLLNPQDIESVSVLKDAASASIYGARAAFGVVLIT
TKKGKKEQKVQINYNNNFSWSMASRLPDGVSSDKWIRAMNQANVNNGSGQYFKDEHVQAV
DDFIAGRGPSAFYTTDNSITAAGQWAYAGNTDWFDVMYKPSFMQQHNASISGGSDKTTYY
GSIGYKGQDGILQYGTDKYKRINMSFNFSTQITKWLEVTFRTKYNRNTSDYPYTSNFNLG
NIFYEIYRGFPTIPVYLPDGNNFAGIAGSNFNYNFAGLLDGAGRDKTNSDDFWYTAAFNL
TPLAGLSIKGDYTGNKFYQDQTQHGKILYQTMPEESTLSPLSVGTPGGVTKANYGDTYQA
LNLWADYKKSFNDKHNLGVMVGYNQESKKTTKLSVSTSNLFDNNFPVTDLASTYNMPSEE
ATIWAVQGAFFRLNYDYMQKYLLEVNGRYDGSSKYMSGDRWGFFPSVSAGWRISEESFFE
PARNIFDNLKVRASYGSLGNQVTDGNFQYLSFLTSESLAYLMNGGIISGLKAPTLASTNI
TWEKVYTTNIGLDWTMLNGRFTGSFDYYIRDTKGMVVNKTYPAVLGTTGGKENLADMRTK
GMELSLTWNDQIKDVAGSPLDYSISIGISDNTSEITKYDNPTLSLDETHYQGKKIGEIWG
YVTDGFIKDEAEAQEMANKQAFISTTWKPGDIRYADLNGDGKIDRGNNRVGDSGDKKVIG
NTTPRYNFNLNLSGSWKGFDLRLFFQGTMKRDVWLDSPVFWGYKTGIWWANLNDYIIDNS
WSETNTNAYYPIPTWSDRSKQTQTKYLQNGAFIRLKDVTLSYTIPKALINKYGIGQLKVF
VSGQNLWEATGLYKYLDPDAVGRRDNNGNLKVDDNGSVYPFTRSYSFGINVTF