Protein Info for HMPREF1078_RS07670 in Parabacteroides merdae CL09T00C40

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 51 to 79 (29 residues), see Phobius details amino acids 97 to 121 (25 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 167 to 190 (24 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details amino acids 272 to 299 (28 residues), see Phobius details amino acids 319 to 338 (20 residues), see Phobius details amino acids 358 to 377 (20 residues), see Phobius details amino acids 398 to 417 (20 residues), see Phobius details amino acids 423 to 440 (18 residues), see Phobius details PF01554: MatE" amino acids 23 to 182 (160 residues), 111.5 bits, see alignment E=5.3e-36 amino acids 245 to 402 (158 residues), 62.6 bits, see alignment E=5.7e-21 TIGR00797: MATE efflux family protein" amino acids 23 to 410 (388 residues), 179 bits, see alignment E=7.2e-57 PF03023: MurJ" amino acids 89 to 237 (149 residues), 28 bits, see alignment E=1.3e-10 PF14667: Polysacc_synt_C" amino acids 138 to 248 (111 residues), 42.1 bits, see alignment E=1.4e-14

Best Hits

KEGG orthology group: None (inferred from 81% identity to osp:Odosp_0599)

Predicted SEED Role

"conserved hypothetical protein, putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (464 amino acids)

>HMPREF1078_RS07670 MATE family efflux transporter (Parabacteroides merdae CL09T00C40)
MATTTKEMTEGAPLPLILNFTFPLLLGNILQQTYSLVDAAIVGKFLGINDLAAIGASTSV
VFLILGFCNGCCCGFGIPVAQKFGARDYKTMRRYVTVSLQLAALMSIVIAVLTSVYCADI
LRSMQTPENIFHGAYYYLLVTFIGVPCTFFYNLLSSIIRALGDSKTPFWFLLFSTVLNIV
LDLFCILVLGWGVLGAGIATVVSQGVSALLCYFYMYKHFPVLKGTADDRKFRFPLAKNLL
YIGVPMGLQFSITAIGSILLQSANNALGTACVAAFTAAMRIKMFFICAFESLGIAMATYT
GQNYGARKPERIWQGIKASSLLMMIYAVFTFTILMSASDKISLLFVDASETEILKNTVLF
LHVSCYFFPILGLLCILRYTIQGAGYTNLAMLSGVSEMIARTLVSIYAVPIFGFLAVCFG
DPTAWIAADLFLVPAFIYVYRKLKKSLKENYAIPNSSTSNSSVE