Protein Info for HMPREF1078_RS07460 in Parabacteroides merdae CL09T00C40

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF00005: ABC_tran" amino acids 27 to 174 (148 residues), 103.7 bits, see alignment E=1.4e-33 PF13304: AAA_21" amino acids 144 to 208 (65 residues), 29 bits, see alignment E=1e-10

Best Hits

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 81% identity to pdi:BDI_1019)

Predicted SEED Role

"Ferric enterobactin transport ATP-binding protein FepC (TC 3.A.1.14.2)" in subsystem Siderophore Enterobactin (TC 3.A.1.14.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.34

Use Curated BLAST to search for 3.6.3.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>HMPREF1078_RS07460 ABC transporter ATP-binding protein (Parabacteroides merdae CL09T00C40)
MRQDTIHINDLSIGYRTKNDTKLVASHIQARIYSGELTCLLGANGVGKSTLLRTLSAFQP
KLGGEIAVLGRDMDSYSDKELSTTIGVVLTEKCDIRNMSVRELVEMGRSPYTGFWGRLDK
EDKQVVEESIALVRIENLASRMVHTLSDGERQKVMIAKALAQETPVIFLDEPTAFLDFPS
KVEIMQLLHHLTRSTNKTIFLSTHDLELALQIADKIWLMDRTNGITPGTPEDLALSGHLS
GFFARKGIVFDTETGLFRIDNRYSKEIRLIGHGQKYAMVRKALQRNGIRADRHVESPVWI
ETGDLSVGSAFLIHHLDGRTLAADTIESLLQELSV