Protein Info for HMPREF1078_RS06515 in Parabacteroides merdae CL09T00C40

Annotation: sulfate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 56 to 91 (36 residues), see Phobius details amino acids 94 to 118 (25 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 200 to 220 (21 residues), see Phobius details amino acids 254 to 276 (23 residues), see Phobius details amino acids 292 to 314 (23 residues), see Phobius details amino acids 326 to 344 (19 residues), see Phobius details amino acids 350 to 367 (18 residues), see Phobius details amino acids 387 to 415 (29 residues), see Phobius details TIGR00815: sulfate permease" amino acids 13 to 549 (537 residues), 401.4 bits, see alignment E=3.1e-124 PF00916: Sulfate_transp" amino acids 23 to 390 (368 residues), 297.5 bits, see alignment E=1.3e-92 PF01740: STAS" amino acids 451 to 549 (99 residues), 57.6 bits, see alignment E=1e-19

Best Hits

KEGG orthology group: K03321, sulfate permease, SulP family (inferred from 89% identity to pdi:BDI_3031)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (558 amino acids)

>HMPREF1078_RS06515 sulfate permease (Parabacteroides merdae CL09T00C40)
MKNKFDFQPKLVSALKNYSKEKFMTDLMAGIIVGIVALPLAIAFGIASGVSPEKGLITAI
LGGFFVSLLGGCNVQIGGPTGAFIVIVYGIIQNFGIEGLAIATVVAGIILVIMGALKLGT
VIKFIPYPIVVGFTSGIALTIFTTQMKDLFGLTMDKVPADFISKWIAYFEHFDTMNLWSL
LIGLTSIVIIAITPKFSKKIPGSLIAIILMTVVVYVMRYHLGITGIETIGDRFTINASLP
GPETINFNMETINLLLPSAFTIAMLGAIESLLSATVADGVTGDKHNSNTELIAQGAANII
VPVFGGIPVTGAIARTMTNINNGGRTPVAGIIHAIVLLLILLFLGPLTKHIPMACLAGVL
IIVSYNMSEWRTFRSLMKNPKSDVSVLLVTFFLTVIFDLTIAIEVGLLIAMFLFMKRVAE
TTHVSVVKDEIDLSDDGEIHHDEEVLSLPKGVEVYEIDGPFFFGVASKFDDIMHNMGDKP
KIRIIRMRKVPFMDSTGLHNLENLFRLSQAEHIHMILSGVNEHVRRVLVKSGFDKKIGTE
NICSNINEAVAKAHEAIR