Protein Info for HMPREF1078_RS06325 in Parabacteroides merdae CL09T00C40

Annotation: deoxyribose-phosphate aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00126: deoxyribose-phosphate aldolase
  • amino acids 70 to 288 (219 residues), 176.1 bits, E=3.3e-56
• PF01791: DeoC
  • amino acids 104 to 272 (169 residues), 82.7 bits, E=1.6e-27

Best Hits

KEGG orthology group: K01619, deoxyribose-phosphate aldolase [EC: 4.1.2.4] (inferred from 75% identity to pdi:BDI_2970)

Predicted SEED Role

"Deoxyribose-phosphate aldolase (EC 4.1.2.4)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 4.1.2.4)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• superpathway of purine deoxyribonucleosides degradation (4/7 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (1/3 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (3/6 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.4

Protein Sequence (311 amino acids)

>HMPREF1078_RS06325 deoxyribose-phosphate aldolase (Parabacteroides merdae CL09T00C40)
MVHEHDHECGCGHHHHDEDTEHLHTNKYQQAFAKFEAAGTTEEVTGRVKTLLGKHGNDNF
TPDVLKQIHGFIDLTSLTSIDTKESIWKLVDKVNDFEGTRPDVPNVAAICTYPLFVETVK
EALSAQEVKIASVAGGFPSSQTFMEIKIAETAMAVMQGADEIDVVMNLGYFLEENYDELS
EEIQEIKESCRDAKLKVILETGALQTPESIQKAAVLAVYSGADFIKTSTGKGYPGATPEA
VYTMCQVLKKYHSITGKRVGIKVAGGVRTAEEAVRYYTIVKEVLGNDWLNKDLFRIGASS
LVEDIEHRLGK