Protein Info for HMPREF1078_RS05810 in Parabacteroides merdae CL09T00C40

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1159 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF16344: FecR_C" amino acids 49 to 113 (65 residues), 24.4 bits, see alignment 6.9e-09 PF07660: STN" amino acids 67 to 115 (49 residues), 34.8 bits, see alignment (E = 3.3e-12) TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 130 to 1159 (1030 residues), 900.6 bits, see alignment E=1.7e-274 PF13620: CarboxypepD_reg" amino acids 132 to 187 (56 residues), 37.5 bits, see alignment 7.8e-13 PF13715: CarbopepD_reg_2" amino acids 132 to 211 (80 residues), 64.7 bits, see alignment 1.9e-21 PF07715: Plug" amino acids 218 to 344 (127 residues), 72.7 bits, see alignment E=1.1e-23 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 320 to 350 (31 residues), 63.2 bits, see alignment (E = 1.5e-21) PF00593: TonB_dep_Rec" amino acids 550 to 910 (361 residues), 83 bits, see alignment E=1.3e-26

Best Hits

KEGG orthology group: None (inferred from 62% identity to bfs:BF0536)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1159 amino acids)

>HMPREF1078_RS05810 TonB-dependent receptor (Parabacteroides merdae CL09T00C40)
MNNQRIVVSLNLKRTIKIMKLTVLMLAVCLSSVVASTYAQTATLNVSAKNETLEKVLKQI
EKQSEFLFFYNLEEINKNEKISINEKNANIQTVLDAIAAKTGLKYTIKDRHIVLTSEAAP
ASTATTQQNRKVTGTVSDAFGPVAGANVIQKGTTNGTTTDMDGNFSIEVPANATLQISFI
GYIPQDIVVKNQNVINVLLKEDTQALEEVIVVGYGTMKKKDMTGAVASVKMDDTPVATVS
TVSHALAGKAAGLQVSTISAQPGGQSTFRIRGAASSDKAGNDPLIIIDGFPVNSPGSLDS
GNQYSGGNKDNILASINPNDIESIEVLKDASSTAIYGARAGNGVIIVTTKRGKSGAAKVQ
YSGSASVQQIAKSYEMLDASGFMRATNDYTREQWMRTNGVGIYGGKEATDPSLPALTLPY
TDAQIANPANNTNWFDEISRLGFQTSHNLSITGGNDNTKYLVSGNYFNQDGVIKNNGMTR
YSLRANLDQKLSKYVKMGINLTATRNEYDNVPLGSGQNENAGILVSAAQFNPALPIRDEN
GNYSMNSDASFLPNPVSLLDITDKTTQERLLANAFFEVRPIDGLLLKANFGIDRNYQKLK
QYLPTTTLYGQRENGAASIAQGDNSDYLMELTANYTKQVGDHNFNALVGHSYQLFTYEMF
SGKSNDFITDGFLYNNLGAGNAKRPTVGSSATKSRMASFFGRLNYTFKDRYLLTATLRAD
GSSNFASGERWGFFPSVAAGWRFTEEEFLAPLRNVLSNGKLRLSYGETGNSNVGDKAYSY
YKVGNNNIFGNSMINGVYLSQLGNNVLTWETAREWNVGLDLGFLDGRVNVTAEYYHKVVS
DLLNEQTLLSYNEVNKIIANVGKTQSQGFELTINTTNIRNKDFEWTSDLTFSLYRDKWKE
RDPKWKPNAYDEYNGWMRYYSGYLSDGLVQVGETIDHMPGALPGQVKIKDIDGYVYESDG
SIKVDKHGIPMKTGKPDGKLDDADKVIYGSADPGYLFGFNNTLRWKNFDLNVYFYGQFDK
LSAGSYKKQWLSNNVNDLRRGYNQPTSISDLWSSSNPNGTLPGYFQTESAYGVGDYYYEK
TWFIRCRNITLGYNIPIKTSKHILSNVRVYFDVNNPFTITPYTGLDPETDISSSESAPSQ
LQWAYPNVRTYSFGLDITF