Protein Info for HMPREF1078_RS05625 in Parabacteroides merdae CL09T00C40

Annotation: metal ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 55 (20 residues), see Phobius details amino acids 61 to 78 (18 residues), see Phobius details amino acids 90 to 111 (22 residues), see Phobius details amino acids 131 to 150 (20 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 190 to 210 (21 residues), see Phobius details amino acids 217 to 239 (23 residues), see Phobius details amino acids 245 to 265 (21 residues), see Phobius details PF00950: ABC-3" amino acids 5 to 259 (255 residues), 235.4 bits, see alignment E=8.4e-74 PF01032: FecCD" amino acids 55 to 257 (203 residues), 39.7 bits, see alignment E=3.3e-14

Best Hits

Swiss-Prot: 39% identical to Y2045_SYNY3: Uncharacterized membrane protein slr2045 (slr2045) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K09816, zinc transport system permease protein (inferred from 88% identity to pdi:BDI_3148)

Predicted SEED Role

"Zinc ABC transporter, inner membrane permease protein ZnuB" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (267 amino acids)

>HMPREF1078_RS05625 metal ABC transporter permease (Parabacteroides merdae CL09T00C40)
MDLLQYGFFQHALLGSLLTAIACGIVGTYIVSRRLVFISGGITHASFGGLGLGFYLGMNP
ILMAMLFSVLSAFGVEWASKTQNVREDSAIAGIWSLGMALGVIFIFLTPGYAPNLSAYLF
GNILTVSTGDIIWIAALALLLVILFSLFLREIVYVAFDRDFALTQGVPVKCIEYVMMCCI
AVTIVLSIRLVGIMLLMSLLTLPQITVNLFTSDFKKIIFGSIAIGFLGCVFGLVLSYLLN
VPSGAFIILVLVLFFLIVKAIKAVLKR