Protein Info for HMPREF1078_RS05015 in Parabacteroides merdae CL09T00C40

Annotation: PfkB family carbohydrate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 156 to 276 (121 residues), 83.1 bits, E=1.2e-27

Best Hits

KEGG orthology group: None (inferred from 74% identity to bvu:BVU_2607)

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• ribose phosphorylation (1/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.15

Use Curated BLAST to search for 2.7.1.15

Protein Sequence (293 amino acids)

>HMPREF1078_RS05015 PfkB family carbohydrate kinase (Parabacteroides merdae CL09T00C40)
MNTHNLCCIGHITLDKIVTPKRTLHMPGGTSFYFAHGMSKLDTSDFLLVTALAVSEMDAV
EEIRRKGIDVKVLPSTHSVYFENTYGENQNNRTQRVLAKADPFTVEGLQDVDARIYHLGS
LLADDFSLDVIKYLSTKGMLSVDAQGYLREVRGENVFAVDWPEKEEALKYIHILKANEHE
TEVLTGCKNPREAALKLANWGVKEVLLTLGSMGSVIYADGEFHEIPAYPPTEIVDATGCG
DTYMAGYLYMRNKGASYKEAGCFAAAMCTIKLEASGPFGGTEKDVWDIIERYK