Protein Info for HMPREF1078_RS04050 in Parabacteroides merdae CL09T00C40

Annotation: alginate lyase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 693 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF05426: Alginate_lyase" amino acids 88 to 288 (201 residues), 50.3 bits, see alignment E=5e-17 PF13229: Beta_helix" amino acids 494 to 628 (135 residues), 55.7 bits, see alignment E=9.4e-19 amino acids 497 to 668 (172 residues), 64.4 bits, see alignment E=2e-21 PF05048: NosD" amino acids 517 to 669 (153 residues), 43.4 bits, see alignment E=5.5e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (693 amino acids)

>HMPREF1078_RS04050 alginate lyase family protein (Parabacteroides merdae CL09T00C40)
MRHNIRFLLIVTMLLLVTGIGTAQKFVHPGIDMNSADLEYMRNQVLAGKQPWKDAYDLLK
EKTPLDFQVKPFAHVISGPYSQPDIGGKDLSQSARMAYSCAVLWYISREECYAEIVIDII
EKWANTLRSFDENNAKLLVALTGYEFCNAAEILRYNYPGWKKIDTENMTRLMMSAFYPTI
RYYFPVANGNWDGAIMHTLLAIAVFTDNRELFDNAVYHYLHANANGSLIKYIYPTGQCQE
TRRDQGHVQMGLYEFSGAARIAYTQGVDLFSAADNRLALGLEYSARFICGDSVYAYGVPS
QRERFKYRAGFEHCIDHFTAKGVNMPYLKELCSRTNMNNPANALWKLTAFREEFRQKPSE
LVDIQESNIAYHAGATLEQAQPVGHSVIEVNNREDLQAVLNTNAGSGKTLFLRAGEYRLK
QSLTIPSDIHICGEGRSTVLICEPTIRTAAILLGDLDAKNITIENLVVDGSKEHQEAYDP
NSGRFYRTGRYSNALAGISMRGEAGHAFSNIKLKNLTVINFSRSGVYISDAEGIEIDHCD
FTENGAHVVPGPRLQHNLMIQHSSNIMIKDSRFDTSIRGCGLVLDHCKSLKVENCEIARN
GWHGLLMAECHNGKIENCLVEGNDGCGFMGEYLHDGSNLIQIRHNKIQYNNEYGIRAFGM
KETDIKDNLYRWNGKEKRQEWLSSEKKLQLEQL