Protein Info for HMPREF1078_RS03620 in Parabacteroides merdae CL09T00C40

Annotation: TldD/PmbA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF01523: PmbA_TldD_1st" amino acids 69 to 133 (65 residues), 55.8 bits, see alignment E=6.5e-19 PF19290: PmbA_TldD_2nd" amino acids 159 to 265 (107 residues), 54.2 bits, see alignment E=3e-18 PF19289: PmbA_TldD_3rd" amino acids 275 to 508 (234 residues), 226.1 bits, see alignment E=4.6e-71

Best Hits

KEGG orthology group: K03568, TldD protein (inferred from 89% identity to pdi:BDI_0919)

Predicted SEED Role

"TldD protein, part of TldE/TldD proteolytic complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (510 amino acids)

>HMPREF1078_RS03620 TldD/PmbA family protein (Parabacteroides merdae CL09T00C40)
MKINRRDFIKTGGMVMLGSLAVPSFLGSCTGNKVDQATGISFAQNHFGVSESDMKKVLAA
ALEKGGDYADLFFEHSYRNNIGLQDGAVNRASSNIDFGMGVRVLAGDQTGYAYVENVTLD
EMLKAARTAARIATGSAGKAPVALTEEPIPNNYYGVQTPWDELAVNAKTPYLQKLNDQIF
ALDKRVHKVMASLGDTTSHILFCNSEGQMYYDYRPMVTLGAVCIMENNGKIENSYASRAF
RMGAEFLTDDIIAEVAKEAVEKTSILFQAIKPKGGEMPVVMGAGGSGILLHEAIGHAFEA
DFNRKNTSIFSDQLNKKVCNEHINVVDDGTIPFNRGSVNIDDEGIAGQKTYIVKEGILTS
YLHDRISAKHYGIPSTGNGRRESFRQMPIPRMRATYMEAGNVTEEEMISTVKKGIYASSF
TNGQVQIGAGDFTFFVKDGYLIENGKLTQPIKDINIIGNGPRALADITMVGNNYKMDNGT
WTCGKDGQSCPVTCGMPSALVSKLTVGGEN