Protein Info for HMPREF1078_RS03575 in Parabacteroides merdae CL09T00C40

Annotation: DUF4974 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 transmembrane" amino acids 85 to 105 (21 residues), see Phobius details PF04773: FecR" amino acids 129 to 216 (88 residues), 53.7 bits, see alignment E=2.3e-18 PF16344: FecR_C" amino acids 260 to 323 (64 residues), 60.7 bits, see alignment E=1.1e-20

Best Hits

Predicted SEED Role

"putative anti-sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>HMPREF1078_RS03575 DUF4974 domain-containing protein (Parabacteroides merdae CL09T00C40)
MTNVNIQTEHIIAYLEGKLSKEDSLAFEKQMLDSPELRKEVGDLRFICDTSQMLYLQEKI
DVDNHWKNVSRTMQKNRFRQKIGRYFRYTAAILLIPALISSIYFYQRIYRLENQPIEQVE
LSSAYGLVSKITLPDGSEVWLNSGSKLHYPKQFVGDHRKVYLSGEAYFKVSSDKKHRFDV
ALSNGITVSAYGTEFNINAYEDDDEIQATLANGSIEIRNEKKPIPQVLNPGEQAVYNKIT
DNTKVSDINLYMVTSWKEGKMVFRRTEMAEIAQRLSRHFNVNIILQSKKIFNYKYSATFT
TETFEEILQLLEKTAPIKCTMIEPKQASDYSYTRRTVIIEAR