Protein Info for HMPREF1078_RS03105 in Parabacteroides merdae CL09T00C40

Annotation: CHC2 zinc finger domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1092 PF01807: zf-CHC2" amino acids 5 to 95 (91 residues), 99.5 bits, see alignment E=1.2e-32 PF08275: DNAG_N" amino acids 134 to 253 (120 residues), 91.3 bits, see alignment E=8e-30 PF13155: Toprim_2" amino acids 263 to 314 (52 residues), 28 bits, see alignment 3.5e-10

Best Hits

KEGG orthology group: None (inferred from 81% identity to osp:Odosp_3617)

Predicted SEED Role

"DNA primase (EC 2.7.7.-)" in subsystem DNA-replication or Macromolecular synthesis operon (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1092 amino acids)

>HMPREF1078_RS03105 CHC2 zinc finger domain-containing protein (Parabacteroides merdae CL09T00C40)
MISETTIRKVRELAIEDVLSPYVRLSRKGSTLMGLCPFHTEKTGSFAVTPSKNLFHCFSC
NRGGDSITFIMEKENLSFSAAVEFIARNHNIPVEYISEERSEEQMAKARHRESLLTVLDT
VQTFFLQCLRATDKEESLDARAYAYSRWHEEFCAFAGIGYAPKDGQAFMDFCRSKALNEE
LLYELGMFKRGEDGNTYAMFRQRIMIPVRNRWGRIIAYTARYIGDNRKAPKYINSATSMI
YSKGETVFGIDRAARLRDADYYIIVEGAPDVLRMQSIGYDNTVASLGTAWSDNQFEQLKR
YVSSLCFIPDSDIAEGKPYGPGFEAVMTNGAAAIRKGFHVTVRELPFAEIPSEAEGEVQY
AKNDADSYIRSREDYTSLPEKHFIIWLAQKRFLVAGSMVEERKCVAEIADLLRYIKDQLV
YDQCIEQLSRLHGKVKLWRDAVTQARGEARRRNDKPTAMNEMQREAELLRQFGLFVRENC
YYSIGEDDDEPSRISNFIMEPLFHIEDEINGTRIFRMRNMYNVCRVIELKESELCSLSNF
QQKVGSLGNYVWLAKIDKLNRVKEYLYSKTDTAERIRKLGWNAAEGFFAFGNGIFFAGTF
NAVDDLGIVRGINGKAFYIPATSKIYLNNPEIFQFERLMVHENRNGIKLHDYVGRLMEVF
GENASVAFCYLLATLFRDIIFRRTRHFPILNLFGEKGTGKTTLATSLQSFFLHGVDPPNL
GVTSVPAMNDRVSQAVNTLAVLDEYKNDLDIRKIAYLKGLWGGGGQTKKNTNTDGMAAQT
IVTTGVALCGQDKPTQDMALYTRVIFLAFSKTSFNQNEKRAYEDLVSVCNMGLTHLTLGI
LGHRELFEKNFPEIYSITKRELATKLENETIHDRIFGNWVIPLATFRTLETVIDVPFSYA
ELFDTAIKGIRNQNELAQESSEIADFWSMLQGFQTSGKCIEKAHYRIRYMKSFRPLSVKE
DIEFKEARPILYLNTAAVASLFNSRNAGSTSNRSNWSTIMSYLKSHASYLGLKQDRFTIL
LPSGLPDYTIDIVNGEQVKKVKVNRPKALCFDYLQLKETFGLDLETEVIAEAQEEIAVEQ
QHIVKQEELHFG