Protein Info for HMPREF1078_RS02410 in Parabacteroides merdae CL09T00C40

Annotation: ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 34 to 53 (20 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 117 to 135 (19 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details amino acids 208 to 230 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 67 to 232 (166 residues), 44 bits, see alignment E=3.2e-15 PF00005: ABC_tran" amino acids 278 to 409 (132 residues), 93.1 bits, see alignment E=3.5e-30 PF13304: AAA_21" amino acids 380 to 444 (65 residues), 32.8 bits, see alignment E=1.2e-11

Best Hits

Predicted SEED Role

"Ferric iron ABC transporter, ATP-binding protein" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (460 amino acids)

>HMPREF1078_RS02410 ATP-binding cassette domain-containing protein (Parabacteroides merdae CL09T00C40)
MKKSIFTILSITILILAWQLLTMLVRLPDLVPSIPHLFSTLVALFASGSFYQSVMATVLR
GTIGMSISLMAAMGVSLLFYKCEWIYELFRPLLAIMRSIPVISFILLALIFLNAESIPLI
IAFLTMFPLLTENLTKGIRGQRKEFSIMARQFRIGRWNKLTQVVYPQLKPFLYSGLASAS
GFGWRAIIMGEVLAQCSPGIGGEMKQAQVFIAVPELIAWTIIAILISYLFDRGISWLAKQ
RFPIHYNKHCSKQPVPKGNCDIRIRDISYRYGSDTVLSHFSYTFEKGFIYGITAPSGTGK
TTLLNLIGNILKPAQGEIETDFKTGIAYVFQEPELLSQLTIAENIALPLAAYLKKEIAFE
QAISILQKMELDGFENRFPNELSFGQQQRAAIARALTYPSPLLLMDEPFKGLDEALSRRI
IKRIRERQTENGQTILFTSHNPGELHLFADKTVRLDPTSH