Protein Info for HMPREF1078_RS01685 in Parabacteroides merdae CL09T00C40

Annotation: 3'(2'),5'-bisphosphate nucleotidase CysQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 PF00459: Inositol_P" amino acids 6 to 261 (256 residues), 172.2 bits, see alignment E=8.6e-55 TIGR01331: 3'(2'),5'-bisphosphate nucleotidase" amino acids 11 to 269 (259 residues), 271.9 bits, see alignment E=2.8e-85

Best Hits

KEGG orthology group: K03677, CysQ protein (inferred from 83% identity to pdi:BDI_0792)

Predicted SEED Role

"3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7)" (EC 3.1.3.7)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (271 amino acids)

>HMPREF1078_RS01685 3'(2'),5'-bisphosphate nucleotidase CysQ (Parabacteroides merdae CL09T00C40)
MNNYANYLYIAIRAALDAGKAIMDIYTDPESDFGIERKADNSPLTKADKKAHAIISMALS
VTPFPVLSEEGKETPFAERSGWDMLWIVDPLDGTKEFIKKNGEFTVNIALVKEGVPVLGV
IYVPVRKELYFAADSLGAFKLAEIDYGYQPSMDEIKTKAIRLPMPMGHQGVVVVASRSHQ
TEETTAFIENLRKQGQPVTLISSGSSLKICLVAEGTADVYPRFAPTMEWDTAAGHAIARA
AGCEVYHIDGKTPLKYNKEDLHNPWFIVKPL