Protein Info for HMPREF1078_RS01450 in Parabacteroides merdae CL09T00C40

Annotation: cytochrome c biogenesis protein CcsA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 811 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 65 (22 residues), see Phobius details amino acids 77 to 99 (23 residues), see Phobius details amino acids 207 to 225 (19 residues), see Phobius details amino acids 245 to 264 (20 residues), see Phobius details amino acids 512 to 530 (19 residues), see Phobius details amino acids 538 to 556 (19 residues), see Phobius details amino acids 576 to 592 (17 residues), see Phobius details amino acids 599 to 618 (20 residues), see Phobius details amino acids 636 to 661 (26 residues), see Phobius details amino acids 682 to 706 (25 residues), see Phobius details amino acids 721 to 739 (19 residues), see Phobius details amino acids 746 to 770 (25 residues), see Phobius details amino acids 785 to 804 (20 residues), see Phobius details PF05140: ResB" amino acids 76 to 192 (117 residues), 81.8 bits, see alignment E=5e-27 PF01578: Cytochrom_C_asm" amino acids 570 to 774 (205 residues), 118.5 bits, see alignment E=3.4e-38

Best Hits

KEGG orthology group: None (inferred from 78% identity to pdi:BDI_0627)

Predicted SEED Role

"Putative cytochrome C-type biogenesis protein" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (811 amino acids)

>HMPREF1078_RS01450 cytochrome c biogenesis protein CcsA (Parabacteroides merdae CL09T00C40)
MKTNLERFFSSFVTTIVLLLIYAFGLAVATFIEKYHGTATAKAMVYYSPLFFLLQFLLVV
NFIAATIKHQYLKRGKWGLMLTHFAFIVILLGALTSFLFGEEGILHLREGETSNQIAVRT
SDNTTFHTLPFSVELKKFTLTRYPGSASPSSYESEVIVHVDGEDREERIFMNNVLDVKGY
RFFQASYDQDEHGTILSVNRDVAGRNITYTGYLLLVIGLILCLVGKDSRFMRQSRRLKEL
RKATNVTVLLLALLAVPLSVNAGGKASPMLDAVQKYAVSPEHAALFGALPIQSGSGRMMP
VNTFSSEILRKLHKSDKIGQLNSDQFLLSLLAMPDMWMRVPFIALSNPELAAYYDLTDGE
CAYIQAFDSNGSYKLQEKLEEAYNKMPAQRTRFDKDLMKLDEQLNIFHQLINHQMLNLFP
KEDDPNHKWYAPGDDLSAFTGKDSMFVSRIFDWYLGEVQEGLKSGDWAKADEVVGMIDTY
QQAKNKTLDISPKRMQAELKYNKMDVFRYCKIGYLVLGGLLLVLSFAMLFRRTRWMKVAV
WLLGAGVLVVFHYHMFGMGMRWYIGGYAPWSNSYETMVYVGWATVLAGLLFVRRSTITFA
LATLFGGIILFVSGLNWMDPEINPLVPVLKSPWLMFHVAVIVAAYGFFGISCLIGLTNMV
MMSVAGKKNKEILKARITELSIVGEMALWVGLALMTVGTFLGAVWANESWGRYWGWDPKE
TWALITMVVYAVVTHLHLVKRWNSLWLFNLASVIAFASVLMTFFGVNYFLSGMHSYGQND
NVHGIFTYLYIALGVVIVLAVLSYRRWKTKV