Protein Info for HMPREF1078_RS01445 in Parabacteroides merdae CL09T00C40

Annotation: SUMF1/EgtB/PvdO family nonheme iron enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1331 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF08305: NPCBM" amino acids 31 to 99 (69 residues), 30.3 bits, see alignment 5.9e-11 amino acids 106 to 183 (78 residues), 57.1 bits, see alignment 3.2e-19 PF18582: HZS_alpha" amino acids 738 to 829 (92 residues), 111.3 bits, see alignment 4.4e-36 PF03781: FGE-sulfatase" amino acids 1070 to 1328 (259 residues), 135.7 bits, see alignment E=3.4e-43

Best Hits

KEGG orthology group: None (inferred from 78% identity to pdi:BDI_0626)

Predicted SEED Role

"FIG00898333: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1331 amino acids)

>HMPREF1078_RS01445 SUMF1/EgtB/PvdO family nonheme iron enzyme (Parabacteroides merdae CL09T00C40)
MNKYYLLVSLFLSSSVMVSADPKQKKAETWIDASVKAKTELQAKLKKSGMPIVSTWMKHK
AKAEPFVVDLKGVDKLVLVTAGGPDGTDYDQAVWANARLIKADGTAVWLDEVPYEYGVAG
WAKPKMNTNAYDHEIVIAGKEYKHGVFCHANGTLVYPVGGQYVRFEAEVGIDDTSSGGSV
FFQALNTVSTFVAEELNNKYPEEIGMLGAVLDGLDTWLITPDASVEKQAADNAIARLKDG
AYYSNVAKQIANEKDLNTQIRKYLELVEKVQELYTLQSDLEWLNVEAVKLAFADMKKQKG
YDAAKYEPMLNELVRLEKKGFKGIYNGDEQAIADAKKALECKRAILLANPLLDADKIVAA
RFKVGSKAHQIMTPSLGTQANNWSNQESAGREGFDAEIVELSNLRGDIQMRQVYKPKNGS
SIADLKLHWDGDRVMFTQTQDDKRWNIYEVNLDGTGFKPLVENDEPDLEFYDGTYLPDGR
VIAISNIGYQGVPCVNGSDAVGNMVLYDPKDKSMRRLTFDQDANWNPVIMNNGRVMYTRW
EYTDLTHYYSRIVMHMNPDGTENKALYGSGAMFPNSTFDVQPLPGHGSAFVGIISGHHGV
ARSGRMIIFDPTKGRKSTAGMVQEIPHRNRPIKEEIKDQLVNGVWPQFIKPTPLNDKYFL
VAAKLDPHALWGLYLVDVYDNVTCLMQAEGEGYISPILVRKTKTPPSIPDRVKLNEKEAT
FFIQDIYEGEGLKGIPRGTVKSLRLHAYEYAYVKTRSDHNWHGIQSGWDIKRMLGTVPVE
EDGSVIFKAPANTPISIQPLDKDGVAIQWMRSWVTGQPGEVVSCIGCHEDQNQIAIPKRV
IASQKAPSALTLPEGGTRSFTFDLEVQPILDRACIACHNGEGKAFDLRGGKKDKLGYGTS
YLNLHPYVHRQGGEGDMVVLQPYEYHPNTSELVRLLKKGHHNVKLTDKEWKTLYNWIDYN
APDKGYFNANVLTDLPYKGFDQIKRRQELTDKYANGAGVDWKKEIADYADYLKKQGPITP
VMPEKAAPVKEKTLKVKGWPFGADRIKEMLAKEKETRKVVEIAPGVKVNFVRIPAGEFVM
GSYRGEPDAYPTAKVKIDKAFWMAELETTNEQFNVVFPDHDSRFVDQQWKDHVVQGYPAN
KPEQPVIRVSYNDAMEFCRKLSEKTGLKITLPTEAQWEWACRAGSDQDFWYGDMHADFGK
KDNLADKTTLLFAVYGVDPQPMAKTNPWYKYYTFLPKEESVDDGNLVQVGGKAYEANPFG
LYSMHGNVAEWTRSDYVSYPYNEKTKETSEYKVARGGSYIDRPKYAASHTRKAYYPYQRV
FNVGFRMIIED