Protein Info for HMPREF1078_RS01105 in Parabacteroides merdae CL09T00C40

Annotation: NUDIX domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 163 PF00293: NUDIX" amino acids 31 to 143 (113 residues), 66 bits, see alignment E=1.8e-22

Best Hits

KEGG orthology group: None (inferred from 78% identity to pdi:BDI_1688)

Predicted SEED Role

"Putative Nudix hydrolase YfcD (EC 3.6.-.-)" in subsystem Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.-.-

Use Curated BLAST to search for 3.6.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (163 amino acids)

>HMPREF1078_RS01105 NUDIX domain-containing protein (Parabacteroides merdae CL09T00C40)
MKEEWFPLVDEKGETIGKATRKECHNGSKMLHPVVHLHIFNKAGDLYLQKRSINKDIQPG
KWDTAVGGHIDYGETVEDALHREVREELGITDFIPQFITRYVFESAIEKELVNTYRTIYD
GPVIPDPSELDGGRFWSPSEILENMGKGIFTPNFEREYKRLFM