Protein Info for HMPREF1078_RS01085 in Parabacteroides merdae CL09T00C40

Annotation: 4Fe-4S dicluster domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 529 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 45 to 67 (23 residues), see Phobius details amino acids 111 to 132 (22 residues), see Phobius details amino acids 171 to 197 (27 residues), see Phobius details amino acids 204 to 224 (21 residues), see Phobius details amino acids 313 to 332 (20 residues), see Phobius details PF12801: Fer4_5" amino acids 54 to 95 (42 residues), 37.6 bits, see alignment 9.7e-13 amino acids 188 to 221 (34 residues), 33.3 bits, see alignment (E = 2.1e-11) PF12838: Fer4_7" amino acids 363 to 418 (56 residues), 30.6 bits, see alignment 2e-10 amino acids 450 to 494 (45 residues), 34.9 bits, see alignment 9.9e-12 PF13187: Fer4_9" amino acids 363 to 419 (57 residues), 29.4 bits, see alignment 3.7e-10 amino acids 450 to 494 (45 residues), 28.2 bits, see alignment 8.6e-10 PF12837: Fer4_6" amino acids 474 to 494 (21 residues), 27.5 bits, see alignment (E = 1.2e-09) PF00037: Fer4" amino acids 475 to 495 (21 residues), 27.9 bits, see alignment (E = 8.6e-10)

Best Hits

Predicted SEED Role

"Ferredoxin" in subsystem Soluble cytochromes and functionally related electron carriers

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (529 amino acids)

>HMPREF1078_RS01085 4Fe-4S dicluster domain-containing protein (Parabacteroides merdae CL09T00C40)
MKKRNYLKGLRVLLAILFFVPILLFFVDFSGVLPDSVHRLLHLQLMPALLGGMVGLIVFQ
FLLALVFGRIYCSTICPAGVFQDIINRLFCIGKKKKKGSRRFTYHKPMNRLRYVLLVITA
VMAVFGLSELCLLLDPYSNFGRIAASLFRPIVMWGNNILADLLMKVDNYSLFHVTISTVT
ASGLIAATIALLVFIVMTVFRGRLFCNTICPVGALLSLFSRYSFFRITFDKEACTHCGNC
EHTCKAEAIDSKNLTIDTSRCVDCFNCVSSCAKGGLQYRLQFPGMKQEETVDTQAVKELY
SSQLTVANSRRTFLATSATIAASLPIASAIAEGGKGKMNRKGRKKWPPLTPPGSISLERF
KDKCTGCQICVVRCPSQVLHPTGLEYGLDYMLKPRLAYISSYCNYECTVCSDVCPTGAIK
PLTIEEKTTTQVGIATFFKGRCVVNTEEKDCGACAEHCPTQAVHMVPYKGTLTIPQINPD
LCIGCGGCESICPVRPMRAIIVKSNVEHKFVEKPKEEEIKEIEVDDFGF