Protein Info for HMPREF1078_RS00950 in Parabacteroides merdae CL09T00C40

Annotation: V-type ATP synthase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 585 PF02874: ATP-synt_ab_N" amino acids 10 to 71 (62 residues), 29.2 bits, see alignment E=1.6e-10 PF16886: ATP-synt_ab_Xtn" amino acids 87 to 205 (119 residues), 120.1 bits, see alignment E=7.1e-39 PF00006: ATP-synt_ab" amino acids 215 to 436 (222 residues), 226.8 bits, see alignment E=3.7e-71

Best Hits

KEGG orthology group: K02117, V-type H+-transporting ATPase subunit A [EC: 3.6.3.14] (inferred from 91% identity to pdi:BDI_0827)

Predicted SEED Role

"V-type ATP synthase subunit A (EC 3.6.3.14)" in subsystem V-Type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (585 amino acids)

>HMPREF1078_RS00950 V-type ATP synthase subunit A (Parabacteroides merdae CL09T00C40)
MATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMAEVIKVIGKNAFVQVFESTRG
MRVGDEAEFEGHMLEVTLGPGMLSRNYDGLQNDLDKMEGVFLRRGEYTFPLDNDKLWDFK
PLAKVGDKVTAGGWLGEVDENFQPHKIMVPFTFKGEYTVKSLKEAGQYTIGEVIAVLTDE
TGKDVEVTMIQRWPVKRAITCYKEKPRPYKLLETGVRTIDTVNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELIDPHTGRKLMERTIIIANTSN
MPVAAREASVYTAMTIAEYYRSMGLKVLLMADSTSRWAQALREMSNRLEELPGPDAFPMD
LSAIVANFYARAGYVHLNNGETGSVTFIGTVSPAGGNLKEPVTENTKKVARCFYALEQER
ADRKRYPAVNPIDSYSKYLEYPEFQEYIAGHISPTWIDKVNEIKTRMLRGKEISEQINIL
GDDGVPVEYHVIFWKSELIDFVILQQDAFDAIDAVTPLARQEFMLNKVVKICHAEFKFNT
FLEVMEYFKKMINIFKQMNYSEYESEQFKKFNDQLDALIAEREDK