Protein Info for HMPREF1078_RS00900 in Parabacteroides merdae CL09T00C40
Annotation: efflux RND transporter permease subunit
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 87% identity to pdi:BDI_1605)Predicted SEED Role
"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1038 amino acids)
>HMPREF1078_RS00900 efflux RND transporter permease subunit (Parabacteroides merdae CL09T00C40) MLNKIIYYSLHNRLVVLICSLLLMIAGTYTAFHTDVDVFPDLNAPTVVIMTEANGMAPEE VERLVTFPVETAVNGAMDVRRVRSSSTTGFSVVWVEFDWGTDIYRARQIVSEKLAVVSES LPENVGKPTLGPQSSILGEMMIIGLTVDDSKSGSRIAPTTQMDLRTIADWTIRPRLLSTG GVAQVAVIGGDIKEYQILLDPARMKHYGVSLGEVLAVTRNMNRNANGGVLYEYDNEYIIR GVLSTANAEEIGKGVVKIVGDFPVLLENIATVKIGSKSPKLGTASERAKPAVLITVTKQP NTSTIDLTEKLDAIMADLQKNLPADVHVSTDIFRQSRFIDSSIDNVKNSLFEGSFFVVIV LFLFLMNIRTTVISLVALPLSLLVSILTLHYMGLTINTMSLGGMAIAIGSLVDDAIVDVE NVYKRIRENHLLPSDQQRSILEVVFDASREVRMPILNSTLIIVVSFVPLFFLSGMEGRML VPLGIAFIVALFASTVVALTLTPVLCSYLLNRKPTDKKVEKEAWVARKLKDLYGKALNGA LAHKNMVLGCTIGLFLVALGMFFTLGRSFLPPFNEGSFTINVSSLPGISLEESDEMGRRA EELLMQVPEIQTVARKTGRAELDEHALGVNVSEIEAPFVLKDRSRDAVMNDVREKLSTIS GANIEIGQPISHRIDAMLSGTEANIAIKLFGTDLNLMFTVGNQIKEAIQGIPGLVDLKVE QQIERPQLTITPKRELMAQYGITLPEFEEYVNVMLGGEAVSQVYDNGKTFDLTVKTSDES RATMEDIRNLMIDAGGKKVPLSYVAEIRSVTGPNTINRENVQRKIVISGNVSERDLRSIV NEIQQKIDASIQLPEGYHIEYGGQFESEQAASRTLLLTSLMSLLVIFLLLYNEFKNAKES GVILLNLPLALIGGVFILKLTSGEVSIPAIIGFISLFGIATRNGMLLISHYTHLRTVENV PLKQAVLQGSMDRLNPILMTALSSALALIPLALNGDLPGNEIQSPMATVILGGLLTSTFL NGFIIPIVYLLMNKEDKE