Protein Info for HMPREF1078_RS00685 in Parabacteroides merdae CL09T00C40

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 PF00753: Lactamase_B" amino acids 22 to 126 (105 residues), 53.5 bits, see alignment E=1.6e-18

Best Hits

KEGG orthology group: K06897, (no description) (inferred from 62% identity to bth:BT_1410)

Predicted SEED Role

"7,8 dihydropteroate synthase (methanopterin)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (268 amino acids)

>HMPREF1078_RS00685 MBL fold metallo-hydrolase (Parabacteroides merdae CL09T00C40)
MHYKITTLVENAVYRRNLQAEHGLSLLIENNGYKILFDTGQSDLFIRNATLSDIEIAEVD
FLILSHGHSDHTGGLRHFLSVNKKASVICKQEALYRKFKDKRENGVIDSNLLDLSRFRFI
TGQTELIPGLFLFPDLPVINPEDTHFERFFTQTPEGVVPDIFNDELVVALIAENTYSVLS
ACSHRGITNILRTIGNCFPGYTFKLLAGGFHIHNAQDEKFSIIADYLKNNLPEQIGICHC
TGIDKYALFRQTFGNRVFYNYTGNTFYL