Protein Info for HMPREF1078_RS00645 in Parabacteroides merdae CL09T00C40

Annotation: DUF1080 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1150 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF13646: HEAT_2" amino acids 359 to 429 (71 residues), 28.2 bits, see alignment 3.9e-10 PF03130: HEAT_PBS" amino acids 396 to 421 (26 residues), 13.7 bits, see alignment (E = 1.7e-05) PF06439: 3keto-disac_hyd" amino acids 741 to 939 (199 residues), 145.8 bits, see alignment E=3.2e-46 amino acids 957 to 1147 (191 residues), 148.1 bits, see alignment E=6.3e-47

Best Hits

KEGG orthology group: None (inferred from 73% identity to pdi:BDI_1153)

Predicted SEED Role

"FIG00896849: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1150 amino acids)

>HMPREF1078_RS00645 DUF1080 domain-containing protein (Parabacteroides merdae CL09T00C40)
MRKAYISIAALLLCGSMLMAQTPANRTAKTTAADVLAQMPAAKQAAYNKLIGDLSSTGEE
GVLMLVNMINAPGKGSNANVDYALSGLTHYVMAKGEENARLVTAKAYLKALEMVNERETK
AFIIRQLQMLGKDECIDVLASYLNDESLSGPAARALASNGSQKAGQALVAALKSRTGSSK
TQKDVIRAIADARVDGAEPVLLVLQGASDPNMQKEVLYALSCVGSSNSLPVLAKAAENAG
YTMEVTGANEAYIALLKRLVQSDRDAVMKAAKKLQKAAAKAGQEQTREAALQILLAAEEP
AKVSKMVIAAMKDPSKNYRNAALSYASGFADKELYIELMKMVPKAKPELKIDILNWIGRE
AKKPVKHDIIQNLEIRFDLPAKQILLEQLGDVNFDVKQAATWTLVKIGDKSYIPSLAELL
KSNDKQVVLLGQDALAAFPGDIDGAVAKAVSSAANAGKIAGLELLAMRKATANINTVLDQ
IQIGSPEVKAAAYVALKDVVGERDITNMCGMLETADALAVPPMQRAVISALSSLPVADRV
ETVTRRMLQAGNKDYLYYLVLASTGQPDALATVVKGFRSNTGVKRDAAFEALLNWKGIEV
ADELYTICKESPSSNYFDPALTTYVKLVSNPAFTGENRLLSLRKAMEIAKTDAQKIAILQ
QIEKTGTFLGMLYAGEFLDQKPVQQAAANAVMNIALGNKEYMGANVRTLLNKVMEVLDNP
DAGYQREAIKKHLAEMPQGEGFVSLFNGKDLTGWKGLVQNPIARAKMKPGQLAKEQAKAD
EVMRKGWSVEDGMLIFNGKGDNLCTEKQYGDFEMYVDWMLDPAGPEADAGIYLRGTPQVQ
IWDTSRVNVGAQVGSGGLYNNQMNESKPTKVADNKLGEWNSFYIKMVGDRVTVVLNGEKV
VDDVILENYWDRKLPIFPVEQIELQAHGSKVYYRNIYVKELERKEPFKLSAEEEKEGFKV
LFDGTNMHEWTGNTVDYTLEDGCISMIPSKSYGGNLYTKDEYGNFVYRFEFQLTPGANNG
VGIRTPMEGDAAYVGMEIQILDCEHPIYKDITPLQHHGSVYGIIPAKAEHHSAFKPAGEW
NYEEIVANGDNIKVTVNGVVIMEGNIREATKNGTADHKEHPGLFNKKGHIGFLGHGSPVK
FRNIRIKELK